| Literature DB >> 19768706 |
Xiaoqin Zhu1, Shuangmu Zhuo, Liqin Zheng, Kecheng Lu, Xingshan Jiang, Jianxin Chen, Bifang Lin.
Abstract
The morphological alterations of human cutaneous normal scar were quantitatively analyzed using multiphoton microscopy (MPM) based on two-photon excited fluorescence and second harmonic generation. High-contrast, high-resolution images of normal scar and uninjured skin were obtained for comparison. In addition, some quantitative parameters have been extracted to quantitatively discriminate between normal scar and uninjured skin. The MPM combined with quantitative method enable a better understanding of microstructual alterations of the epidermis, elastic fiber, and collagen in normal scar. It may lead the way to making know the mechanism of normal scar formation and identifying feasible therapeutic options. 2010 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.Entities:
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Year: 2010 PMID: 19768706 DOI: 10.1002/jbio.200910058
Source DB: PubMed Journal: J Biophotonics ISSN: 1864-063X Impact factor: 3.207