Literature DB >> 19767287

Bradycardia and severe hypotension caused by wild honey poisoning.

Laxman Dubey1, Arun Maskey, Shyam Regmi.   

Abstract

Wild honey is taken as an alternative medicine for the treatment of gastrointestinal diseases as well as for coronary artery disease. However, wild honey made from the nectar of some species of rhododendron may be poisonous. The cause of the poisoning is the toxin grayanotoxin. Grayanotoxin is a naturally occurring sodium channel toxin that causes life-threatening bradycardia, hypotension, and altered mental status. Complete heart blocks may occur in some patients. We present an interesting case of bradycardia and hypotension due to wild honey ingestion. The symptoms, mechanism, and management of wild honey poisoning are discussed.

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Year:  2009        PMID: 19767287

Source DB:  PubMed          Journal:  Hellenic J Cardiol        ISSN: 1109-9666


  5 in total

1.  Clinical characteristics and outcomes of patients with grayanotoxin poisoning after the ingestion of mad honey from Nepal.

Authors:  Chang Hwan Sohn; Dong Woo Seo; Seung Mok Ryoo; Jae Ho Lee; Won Young Kim; Kyoung Soo Lim; Bum Jin Oh
Journal:  Intern Emerg Med       Date:  2013-09-12       Impact factor: 3.397

Review 2.  Possible complication of bee stings and a review of the cardiac effects of bee stings.

Authors:  Prabha Nini Gupta; B Krishna Kumar; Praveen Velappan; M D Sudheer
Journal:  BMJ Case Rep       Date:  2016-11-01

3.  Electroencephalographic and behavioral effects of intracerebroventricular or intraperitoneal injections of toxic honey extract in adult Wistar rats and GAERS.

Authors:  Pinar Kuru; Merve Torun; Hande Melike Halac; Gozde Temiz; Ece Iskender; Tugba Karamahmutoglu; Medine Gulcebi Idrizoglu; Filiz Yilmaz Onat
Journal:  Neurol Sci       Date:  2014-08-14       Impact factor: 3.307

Review 4.  Grayanotoxin poisoning: 'mad honey disease' and beyond.

Authors:  Suze A Jansen; Iris Kleerekooper; Zonne L M Hofman; Isabelle F P M Kappen; Anna Stary-Weinzinger; Marcel A G van der Heyden
Journal:  Cardiovasc Toxicol       Date:  2012-09       Impact factor: 3.231

Review 5.  Mad honey: uses, intoxicating/poisoning effects, diagnosis, and treatment.

Authors:  Sana Ullah; Shahid Ullah Khan; Tawfik A Saleh; Shah Fahad
Journal:  RSC Adv       Date:  2018-05-22       Impact factor: 4.036

  5 in total

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