Literature DB >> 19767052

Diagnosis of gastrointestinal anastomotic dehiscence after hospital discharge: Impact on patient management and outcome.

Dana A Telem1, Malini Sur, Parissa Tabrizian, Tiffany E Chao, Scott Q Nguyen, Edward H Chin, Celia M Divino.   

Abstract

BACKGROUND: Anastomotic leaks are inevitable complications of gastrointestinal surgery. Early hospital discharge protocols have increased concern regarding outpatient presentation with anastomotic leaks.
METHODS: One hundred anastomotic leaks in 5,387 intestinal operations performed at a single institution from 2002 to 2007 were identified from a prospectively maintained database. Statistical analysis was conducted by the unpaired t test, Chi-square test, and analysis of variance.
RESULTS: Overall anastomotic leak with a rate of 2.6% for colonic and 0.53% for small bowel anastomoses. Mean time to anastomotic leak diagnosis was 7 days after operation. Twenty-six patients presented after discharge, with mean time to diagnosis 12 days versus 6 days for inpatients (P<.05). Patients presenting after hospital discharge were younger, had lesser American Society of Anesthesiologists (ASA) scores, and were more likely to have colon cancer and less likely to have Crohn's disease. Ninety-two patients required operative management, of whom 81 (90%) underwent diversion. No difference in management, intensive care unit (ICU) requirement, duration of stay, or mortality between inpatient versus outpatient diagnosis was demonstrated. Follow-up at mean of 36 months demonstrated no difference in readmission, reoperation, or mortality rate between outpatient and inpatient diagnosis. Restoration of gastrointestinal continuity was achieved in 61-67% in the outpatient and 59% in the inpatient group (P=NS).
CONCLUSION: Outpatient presentation delays diagnosis but does not alter management or clinical outcome, or decrease the probability of ostomy reversal. Prolonging hospital stay to capture patients who develop anastomotic leak seems to be unwarranted. For patients requiring operative management, we recommend diversion as the safest option with a subsequent 61% reversal rate. Copyright (c) 2010 Mosby, Inc. All rights reserved.

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Year:  2009        PMID: 19767052     DOI: 10.1016/j.surg.2009.06.034

Source DB:  PubMed          Journal:  Surgery        ISSN: 0039-6060            Impact factor:   3.982


  5 in total

Review 1.  [Perioperative complications of the lower gastrointestinal tract : Prevention, recognition and treatment].

Authors:  Y Kulu; M W Büchler; A Ulrich
Journal:  Chirurg       Date:  2015-04       Impact factor: 0.955

Review 2.  [Diagnosis and definition of anastomotic leakage from the surgeon's perspective].

Authors:  T Welsch; M von Frankenberg; J Schmidt; M W Büchler
Journal:  Chirurg       Date:  2011-01       Impact factor: 0.955

3.  The Science of Anastomotic Healing.

Authors:  Ryan B Morgan; Benjamin D Shogan
Journal:  Semin Colon Rectal Surg       Date:  2022-03-08

4.  Management of anastomotic leak: lessons learned from a large colon and rectal surgery training program.

Authors:  Jennifer Blumetti; Vivek Chaudhry; Jose R Cintron; John J Park; Slawomir Marecik; Jacqueline L Harrison; Leela M Prasad; Herand Abcarian
Journal:  World J Surg       Date:  2014-04       Impact factor: 3.352

5.  The burden of gastrointestinal anastomotic leaks: an evaluation of clinical and economic outcomes.

Authors:  Jeffrey Hammond; Sangtaeck Lim; Yin Wan; Xin Gao; Anuprita Patkar
Journal:  J Gastrointest Surg       Date:  2014-06       Impact factor: 3.452

  5 in total

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