Literature DB >> 19766430

In vivo selection of carbapenem-resistant Klebsiella pneumoniae by OmpK36 loss during meropenem treatment.

Wonkeun Song1, Borum Suh, Jun Yong Choi, Seok Hoon Jeong, Eun Hee Jeon, Young Ki Lee, Seong Geun Hong, Kyungwon Lee.   

Abstract

We recovered a carbapenem-resistant Klebsiella pneumoniae isolate H224 under in vivo meropenem selection pressure. Insertional inactivation of a major porin gene, ompK36, by IS5 element might play a role in acquiring carbapenem resistance in this strain harboring plasmid-borne DHA-1 AmpC beta-lactamase.

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Year:  2009        PMID： 19766430     DOI： 10.1016/j.diagmicrobio.2009.08.010

Source DB:  PubMed          Journal:  Diagn Microbiol Infect Dis        ISSN： 0732-8893            Impact factor:   2.803


  9 in total

1.  Large oligoclonal outbreak due to Klebsiella pneumoniae ST14 and ST26 producing the FOX-7 AmpC β-lactamase in a neonatal intensive care unit.

Authors:  Fabio Arena; Tommaso Giani; Elisa Becucci; Viola Conte; Giacomo Zanelli; Marco Maria D'Andrea; Giuseppe Buonocore; Franco Bagnoli; Alessandra Zanchi; Francesca Montagnani; Gian Maria Rossolini
Journal:  J Clin Microbiol       Date:  2013-10-02       Impact factor: 5.948

2.  Rapid induction of high-level carbapenem resistance in heteroresistant KPC-producing Klebsiella pneumoniae.

Authors:  Sheila Adams-Sapper; Shantell Nolen; Grace Fox Donzelli; Mallika Lal; Kunihiko Chen; Livia Helena Justo da Silva; Beatriz M Moreira; Lee W Riley
Journal:  Antimicrob Agents Chemother       Date:  2015-03-23       Impact factor: 5.191

Review 3.  Adaptive and mutational resistance: role of porins and efflux pumps in drug resistance.

Authors:  Lucía Fernández; Robert E W Hancock
Journal:  Clin Microbiol Rev       Date:  2012-10       Impact factor: 26.132

4.  Characterization of carbapenem-nonsusceptible Klebsiella pneumoniae bloodstream isolates at a Taiwanese hospital: clinical impacts of lowered breakpoints for carbapenems.

Authors:  N Y Lee; J J Wu; S H Lin; W C Ko; L H Tsai; J J Yan
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2012-01-18       Impact factor: 3.267

5.  OmpK26, a novel porin associated with carbapenem resistance in Klebsiella pneumoniae.

Authors:  Laura García-Sureda; Antonio Doménech-Sánchez; Mariette Barbier; Carlos Juan; Joan Gascó; Sebastián Albertí
Journal:  Antimicrob Agents Chemother       Date:  2011-08-01       Impact factor: 5.191

6.  Mutations of the ompK36 porin gene and promoter impact responses of sequence type 258, KPC-2-producing Klebsiella pneumoniae strains to doripenem and doripenem-colistin.

Authors:  Cornelius J Clancy; Liang Chen; Jae H Hong; Shaoji Cheng; Binghua Hao; Ryan K Shields; Annie N Farrell; Yohei Doi; Yanan Zhao; David S Perlin; Barry N Kreiswirth; M Hong Nguyen
Journal:  Antimicrob Agents Chemother       Date:  2013-08-12       Impact factor: 5.191

7.  An Increase in the clinical isolation of acquired AmpC β-lactamase-producing Klebsiella pneumoniae in Korea from 2007 to 2010.

Authors:  Min-Jeong Park; Taek-Kyung Kim; Wonkeun Song; Jae-Seok Kim; Han-Sung Kim; Jacob Lee
Journal:  Ann Lab Med       Date:  2013-08-08       Impact factor: 3.464

8.  Combined use of the modified Hodge test and carbapenemase inhibition test for detection of carbapenemase-producing Enterobacteriaceae and metallo-β-lactamase-producing Pseudomonas spp.

Authors:  Wonkeun Song; Seong Geun Hong; Dongeun Yong; Seok Hoon Jeong; Hyun Soo Kim; Han-Sung Kim; Jae-Seok Kim; Il Kwon Bae
Journal:  Ann Lab Med       Date:  2015-02-12       Impact factor: 3.464

9.  Stress-Adaptive Responses Associated with High-Level Carbapenem Resistance in KPC-Producing Klebsiella pneumoniae.

Authors:  Sheila Adams-Sapper; Adam Gayoso; Lee W Riley
Journal:  J Pathog       Date:  2018-03-19
  9 in total

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