Literature DB >> 19766427

The Helicobacter pylori Mfd protein is important for antibiotic resistance and DNA repair.

Gin Hyug Lee1, Jin-Yong Jeong, Jun-Won Chung, Won-Hee Nam, Sun-Mi Lee, Jhang-Ho Pak, Kee Don Choi, Ho June Song, Hwoon-Yong Jung, Jin-Ho Kim.   

Abstract

A Helicobacter pylori mutant defective in a putative mfd gene was constructed and characterized. The mfd gene is required for DNA repair and is involved in DNA recombination processes. The mfd mutant strain displayed a greatly increased susceptibility to antibiotics, indicating that this gene plays a significant role in the antibiotic resistance of H. pylori strain J99.

Entities:  

Mesh：

Substances：

Year:  2009        PMID： 19766427     DOI： 10.1016/j.diagmicrobio.2009.08.007

Source DB:  PubMed          Journal:  Diagn Microbiol Infect Dis        ISSN： 0732-8893            Impact factor:   2.803


  14 in total

1.  Nucleotide excision repair (NER) machinery recruitment by the transcription-repair coupling factor involves unmasking of a conserved intramolecular interface.

Authors:  Alexandra M Deaconescu; Anastasia Sevostyanova; Irina Artsimovitch; Nikolaus Grigorieff
Journal:  Proc Natl Acad Sci U S A       Date:  2012-02-13       Impact factor: 11.205

Review 2.  From Mfd to TRCF and Back Again-A Perspective on Bacterial Transcription-coupled Nucleotide Excision Repair.

Authors:  Alexandra M Deaconescu; Margaret M Suhanovsky
Journal:  Photochem Photobiol       Date:  2016-12-27       Impact factor: 3.421

Review 3.  Recombination and DNA repair in Helicobacter pylori.

Authors:  Marion S Dorer; Tate H Sessler; Nina R Salama
Journal:  Annu Rev Microbiol       Date:  2011       Impact factor: 15.500

Review 4.  Targeting evolution to inhibit antibiotic resistance.

Authors:  Houra Merrikh; Rahul M Kohli
Journal:  FEBS J       Date:  2020-06-08       Impact factor: 5.542

Review 5.  Mfd - at the crossroads of bacterial DNA repair, transcriptional regulation and molecular evolvability.

Authors:  Alexandra M Deaconescu
Journal:  Transcription       Date:  2021-10-21

6.  Identification of genes involved in low aminoglycoside-induced SOS response in Vibrio cholerae: a role for transcription stalling and Mfd helicase.

Authors:  Zeynep Baharoglu; Anamaria Babosan; Didier Mazel
Journal:  Nucleic Acids Res       Date:  2013-12-06       Impact factor: 16.971

7.  Stationary-Phase Mutagenesis in Stressed Bacillus subtilis Cells Operates by Mfd-Dependent Mutagenic Pathways.

Authors:  Martha Gómez-Marroquín; Holly A Martin; Amber Pepper; Mary E Girard; Amanda A Kidman; Carmen Vallin; Ronald E Yasbin; Mario Pedraza-Reyes; Eduardo A Robleto
Journal:  Genes (Basel)       Date:  2016-07-05       Impact factor: 4.096

8.  The bacterial DNA repair protein Mfd confers resistance to the host nitrogen immune response.

Authors:  Elisabeth Guillemet; Alain Leréec; Seav-Ly Tran; Corinne Royer; Isabelle Barbosa; Philippe Sansonetti; Didier Lereclus; Nalini Ramarao
Journal:  Sci Rep       Date:  2016-07-20       Impact factor: 4.379

9.  Molecular determinants for dsDNA translocation by the transcription-repair coupling and evolvability factor Mfd.

Authors:  Cheng Zhang; Margaret M Suhanovsky; Christiane Brugger; David D Kim; Amy N Sinclair; Dmitry Lyumkis; Alexandra M Deaconescu
Journal:  Nat Commun       Date:  2020-07-27       Impact factor: 14.919

10.  The Bacterial Mfd Protein Prevents DNA Damage Induced by the Host Nitrogen Immune Response in a NER-Independent but RecBC-Dependent Pathway.

Authors:  Claire Darrigo; Elisabeth Guillemet; Rozenn Dervyn; Nalini Ramarao
Journal:  PLoS One       Date:  2016-10-06       Impact factor: 3.240
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.