Literature DB >> 19765633

Levels of neuregulin 1 and 3 proteins in Brodmann's area 46 from subjects with schizophrenia and bipolar disorder.

Simone Boer1, Michael Berk, Brian Dean.   

Abstract

Neuregulin (NRG) 1Ialpha and NRG3 proteins levels were measured in Brodmann's area 46 from 20 subjects with schizophrenia, 8 subjects with bipolar 1 disorder and 20 age-sex matched control subjects. Protein levels of both NRG1Ialpha and NRG3 were unchanged in both psychiatric illnesses. These data suggest any change in NRG1Ialpha and NRG3 expression in schizophrenia or bipolar 1 disorder do not result in changes levels in levels of those proteins Brodmann's area 46.

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Year:  2009        PMID: 19765633     DOI: 10.1016/j.neulet.2009.09.019

Source DB:  PubMed          Journal:  Neurosci Lett        ISSN: 0304-3940            Impact factor:   3.046


  4 in total

1.  Differential neuregulin 1 cleavage in the prefrontal cortex and hippocampus in schizophrenia and bipolar disorder: preliminary findings.

Authors:  Ketan Marballi; Dianne Cruz; Peter Thompson; Consuelo Walss-Bass
Journal:  PLoS One       Date:  2012-05-10       Impact factor: 3.240

2.  Elevated peripheral expression of neuregulin-1 (NRG1) mRNA isoforms in clozapine-treated schizophrenia patients.

Authors:  Md Shaki Mostaid; Ting Ting Lee; Gursharan Chana; Suresh Sundram; Cynthia Shannon Weickert; Christos Pantelis; Ian Everall; Chad Bousman
Journal:  Transl Psychiatry       Date:  2017-12-11       Impact factor: 6.222

3.  Schizophrenia-associated HapICE haplotype is associated with increased NRG1 type III expression and high nucleotide diversity.

Authors:  C S Weickert; Y Tiwari; P R Schofield; B J Mowry; J M Fullerton
Journal:  Transl Psychiatry       Date:  2012-04-17       Impact factor: 6.222

4.  Neuregulin 1 Type I Overexpression Is Associated with Reduced NMDA Receptor-Mediated Synaptic Signaling in Hippocampal Interneurons Expressing PV or CCK.

Authors:  Dimitrios Kotzadimitriou; Wiebke Nissen; Melinda Paizs; Kathryn Newton; Paul J Harrison; Ole Paulsen; Karri Lamsa
Journal:  eNeuro       Date:  2018-05-08
  4 in total

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