| Literature DB >> 19762271 |
V Puente1, O De Fabregues, C Oliveras, G Ribera, C Pont-Sunyer, R Vivanco, G Cucurella, E Giralt, T Delgado, C Garcia, A Seoane, R Campo.
Abstract
Symptom control, daily "on" time, and quality of life (QoL) of nine patients with Advanced Parkinson's Disease was assessed following 18-months treatment with Continuous Intraduodenal Levodopa Infusion (CIDLI). Patients had severe motor fluctuations and dyskinesias and had previously received treatment with oral levodopa and dopamine agonists. There were significant improvements in patients' symptoms on the Unified Parkinson's Disease Rating Scale, and QoL (Parkinson's Disease QoL Questionnaire; Schwab & England Capacity for Daily Living Scale; p < 0.05). Mean (+/-SD) daily "on" time increased from 6.1 +/- 1.9 to 12.0 +/- 3.4 h (p < 0.05). Improved QoL in APD was associated with CIDLI-related improvements in symptom control and increase in daily "on" time. Copyright (c) 2009. Published by Elsevier Ltd.Entities:
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Year: 2009 PMID： 19762271 DOI： 10.1016/j.parkreldis.2009.07.015
Source DB: PubMed Journal: Parkinsonism Relat Disord ISSN： 1353-8020 Impact factor: 4.891