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Literature DB >> 19761537

Fractional exhaled nitric oxide in asthma: an update.

Alessandra Sandrini¹, D Robin Taylor, Paul S Thomas, Deborah H Yates.

Abstract

In asthma, clinical symptoms and lung function are insensitive in reflecting the underlying airway inflammation, and monitoring of this process has only recently become available. Fractional exhaled nitric oxide (Fe(NO)) is now recognized as a reliable surrogate marker of eosinophilic airway inflammation and offers the advantage of being completely non-invasive and very easy to obtain. This review summarizes the clinical use of Fe(NO) in asthma. It covers the relationship between Fe(NO) and the underlying eosinophilic inflammation, the pathophysiology and production of Fe(NO), technical aspects of Fe(NO) measurement and potential confounding factors in interpreting levels. Fe(NO) reference values and the role of Fe(NO) in asthma assessment, diagnosis and management are also discussed.

Entities: Chemical Disease

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Year: 2009 PMID： 19761537 DOI： 10.1111/j.1440-1843.2009.01616.x

Source DB: PubMed Journal: Respirology ISSN： 1323-7799 Impact factor: 6.424

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Cited

11 in total

1. Evaluation of high-sensitivity serum CRP levels compared to markers of airway inflammation and allergy as predictors of methacholine bronchial hyper-responsiveness in children.

Authors: Galit Livnat; Ronen Bar Yoseph; Vered Nir; Fahed Hakim; Mordechai Yigla; Lea Bentur
Journal: Lung Date: 2014-10-21 Impact factor: 2.584

2. Investigation of the relationship between IL-6 and type 2 biomarkers in patients with severe asthma.

Authors: Xingnan Li; Annette T Hastie; Michael C Peters; Gregory A Hawkins; Wanda Phipatanakul; Huashi Li; Wendy C Moore; William W Busse; Mario Castro; Serpil C Erzurum; Benjamin Gaston; Elliot Israel; Nizar N Jarjour; Bruce D Levy; Sally E Wenzel; Deborah A Meyers; John V Fahy; Eugene R Bleecker
Journal: J Allergy Clin Immunol Date: 2019-09-09 Impact factor: 10.793

3. Reference ranges and determinant factors for exhaled nitric oxide in a healthy korean elderly population.

Authors: Eun-Jung Jo; Woo-Jung Song; Tae-Wan Kim; Heung-Woo Park; Yoon-Seok Chang; Tae-Bum Kim; Sang-Heon Kim; Gyu-Young Hur; Jae-Hyung Lee; Ho-Joo Yoon; Hae-Sim Park; Nam-Ho Cho; Hee-Bom Moon; Kyung-Up Min; Sang-Heon Cho
Journal: Allergy Asthma Immunol Res Date: 2014-03-31 Impact factor: 5.764

Review 4. Significance of Exhaled Breath Test in Clinical Diagnosis: A Special Focus on the Detection of Diabetes Mellitus.

Authors: Souvik Das; Saurabh Pal; Madhuchhanda Mitra
Journal: J Med Biol Eng Date: 2016-10-11 Impact factor: 1.553

Fractional exhaled nitric oxide in asthma: an update.

1. Evaluation of high-sensitivity serum CRP levels compared to markers of airway inflammation and allergy as predictors of methacholine bronchial hyper-responsiveness in children.

2. Investigation of the relationship between IL-6 and type 2 biomarkers in patients with severe asthma.

3. Reference ranges and determinant factors for exhaled nitric oxide in a healthy korean elderly population.

Review 4. Significance of Exhaled Breath Test in Clinical Diagnosis: A Special Focus on the Detection of Diabetes Mellitus.

5. Pragmatic Markers in the Management of Asthma: A Real-World-Based Approach.

Review 6. Asthma in children and adolescents: a comprehensive approach to diagnosis and management.

Review 7. Diagnosis of allergy and asthma in childhood.

8. Significance of fractional exhaled nitric oxide in chronic eosinophilic pneumonia: a retrospective cohort study.

9. Endotoxin, dust and exhaled nitrogen oxide among hand pickers of coffee; a cross-sectional study.

10. Reference Ranges and Determinant Factors for Fractional Exhaled Nitric Oxide in a Healthy Saudi Adult Population.