Literature DB >> 19760781

Effect of EP4 agonist (ONO-4819CD) for patients with mild to moderate ulcerative colitis refractory to 5-aminosalicylates: a randomized phase II, placebo-controlled trial.

Hiroshi Nakase, Yoshihide Fujiyama, Nobuhide Oshitani, Toru Oga, Kimiko Nonomura, Toshiyuki Matsuoka, Yoshiyasu Esaki, Toshinori Murayama, Satoshi Teramukai, Tsutomu Chiba, Shuh Narumiya.   

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Year:  2010        PMID： 19760781     DOI： 10.1002/ibd.21080

Source DB:  PubMed          Journal:  Inflamm Bowel Dis        ISSN： 1078-0998            Impact factor:   5.325


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  18 in total

1.  Intestinal myofibroblast-specific Tpl2-Cox-2-PGE2 pathway links innate sensing to epithelial homeostasis.

Authors:  Manolis Roulis; Christoforos Nikolaou; Elena Kotsaki; Eleanna Kaffe; Niki Karagianni; Vasiliki Koliaraki; Klelia Salpea; Jiannis Ragoussis; Vassilis Aidinis; Eva Martini; Christoph Becker; Harvey R Herschman; Stefania Vetrano; Silvio Danese; George Kollias
Journal:  Proc Natl Acad Sci U S A       Date:  2014-10-14       Impact factor: 11.205

2.  Prostaglandin E2 promotes intestinal repair through an adaptive cellular response of the epithelium.

Authors:  Hiroyuki Miyoshi; Kelli L VanDussen; Nicole P Malvin; Stacy H Ryu; Yi Wang; Naomi M Sonnek; Chin-Wen Lai; Thaddeus S Stappenbeck
Journal:  EMBO J       Date:  2016-10-24       Impact factor: 11.598

Review 3.  Role of epithelial cells in the pathogenesis and treatment of inflammatory bowel disease.

Authors:  Ryuichi Okamoto; Mamoru Watanabe
Journal:  J Gastroenterol       Date:  2015-07-03       Impact factor: 7.527

Review 4.  Understanding the role of prostaglandin E2 in regulating human platelet activity in health and disease.

Authors:  Eitan A Friedman; Martin L Ogletree; Elias V Haddad; Olivier Boutaud
Journal:  Thromb Res       Date:  2015-05-28       Impact factor: 3.944

Review 5.  Critical roles of G protein-coupled receptors in regulating intestinal homeostasis and inflammatory bowel disease.

Authors:  Zhongsheng Feng; Ruicong Sun; Yingzi Cong; Zhanju Liu
Journal:  Mucosal Immunol       Date:  2022-06-22       Impact factor: 8.701

6.  International Union of Basic and Clinical Pharmacology. CIX. Differences and Similarities between Human and Rodent Prostaglandin E2 Receptors (EP1-4) and Prostacyclin Receptor (IP): Specific Roles in Pathophysiologic Conditions.

Authors:  Xavier Norel; Yukihiko Sugimoto; Gulsev Ozen; Heba Abdelazeem; Yasmine Amgoud; Amel Bouhadoun; Wesam Bassiouni; Marie Goepp; Salma Mani; Hasanga D Manikpurage; Amira Senbel; Dan Longrois; Akos Heinemann; Chengcan Yao; Lucie H Clapp
Journal:  Pharmacol Rev       Date:  2020-10       Impact factor: 25.468

7.  E-type prostanoid receptor 4 drives resolution of intestinal inflammation by blocking epithelial necroptosis.

Authors:  Jay V Patankar; Tanja M Müller; Srinivas Kantham; Miguel Gonzalez Acera; Fabrizio Mascia; Kristina Scheibe; Mousumi Mahapatro; Christina Heichler; Yuqiang Yu; Wei Li; Barbara Ruder; Claudia Günther; Moritz Leppkes; Mano J Mathew; Stefan Wirtz; Clemens Neufert; Anja A Kühl; Jay Paquette; Kevan Jacobson; Raja Atreya; Sebastian Zundler; Markus F Neurath; Robert N Young; Christoph Becker
Journal:  Nat Cell Biol       Date:  2021-07-08       Impact factor: 28.824

8.  Prostaglandin E2 stimulates cAMP signaling and resensitizes human leukemia cells to glucocorticoid-induced cell death.

Authors:  Justine E Roderick; Kayleigh M Gallagher; Leonard C Murphy; Kevin W O'Connor; Katherine Tang; Boyao Zhang; Michael A Brehm; Dale L Greiner; Jun Yu; Lihua Julie Zhu; Michael R Green; Michelle A Kelliher
Journal:  Blood       Date:  2021-01-28       Impact factor: 25.476

Review 9.  E-type prostanoid receptor 4 (EP4) in disease and therapy.

Authors:  Viktoria Konya; Gunther Marsche; Rufina Schuligoi; Akos Heinemann
Journal:  Pharmacol Ther       Date:  2013-03-21       Impact factor: 12.310

Review 10.  Epithelial wound healing in inflammatory bowel diseases: the next therapeutic frontier.

Authors:  Cambrian Y Liu; Candace M Cham; Eugene B Chang
Journal:  Transl Res       Date:  2021-06-12       Impact factor: 10.171
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