| Literature DB >> 19757855 |
Intan Safinar Ismail1, Yuta Nagakura, Yusuke Hirasawa, Takahiro Hosoya, Mohd Izwan Mohd Lazim, Nordin Hj Lajis, Motoo Shiro, Hiroshi Morita.
Abstract
Four new chromone alkaloids, chrotacumines A-D (1-4), consisting of a 5,7-dihydroxy-2-methylchromone, an N-Me piperidine ring, and an ester side chain were isolated from Dysoxylum acutangulum, and their structures including absolute configurations were elucidated on the basis of spectroscopic data interpretation including 2D NMR, CD spectra, and X-ray analysis. The known compound rohitukine (5) showed moderate cytotoxicity against human HL-60 promyelocytic leukemia and HCT-116 colon cancer cells.Entities:
Mesh：
Substances：
Year: 2009 PMID： 19757855 DOI： 10.1021/np9003849
Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050