The Animal Welfare Act, USDA, & research.

In the above discussion, the concept and evolution of IACUC oversight of research facility animal care and use programs and common USDA citations concerning these programs was reviewed. The majority of USDA citations are program-related and involve both IACUC and veterinary care functions. Common IACUC-related citations concern inadequacies involving required information in protocols (such as rationales for the species and numbers used and descriptions of the procedures proposed), searches for alternatives to painful or distressful procedures, and minimization of pain and distress. Common veterinary care citations concern inadequacies involving veterinary care facilities, daily observation of the animals, and veterinary care itself (e.g., maintaining inadequate records or using expired medications). IACUC's are advised to ensure that their program records are comprehensive enough to demonstrate that their facility's animal care and use program complies with the AWA and USDA regulations. The overall ongoing success of self-regulation in the research industry is acknowledged, and APHIS's current concentration on the recognition and alleviation of distress, as well as pain, is noted. In the future, APHIS will continue in its oversight role as IACUC programs continue to evolve in their awareness and application of the advances in pain and distress recognition and management. Together, we will continue to work for the benefit of the animals used in research, whose welfare is so important to the quality of that very research.