BACKGROUND: This study aimed to establish a payer-perspective cost-effectiveness and budget impact model of adjustable gastric banding (AGB) and gastric bypass (GBP) vs. conventional treatment (CT) in patients with a body mass index (BMI) > or = 35 kg x m(-2) and type 2 diabetes mellitus (T2DM) in Austria, Italy, and Spain. METHODS: A health economics model described in a previous publication was applied to resource utilization and cost data in AGB, GBP, and CT from Austria, Italy, and Spain in 2009. RESULTS: The base case time scope is 5 years; the annual discount rate for utilities and costs is 3.5%. In Austria and Italy, both AGB and GBP are cost-saving and are thus dominant in terms of incremental cost-effectiveness ratio compared to CT. In Spain, AGB and GBP yield a moderate cost increase but are cost-effective, assuming a willingness-to-pay threshold of 30,000 euro per quality adjusted life-year. Under worst-case analysis, AGB and GBP remain cost-saving or around breakeven in Austria and Italy and remain cost-effective in Spain. CONCLUSION: In patients with T2DM and BMI > or = 35 kg x m(-2) at 5-year follow-up vs. CT, AGB and GBP are not only clinically effective and safe but represent satisfactory value for money from a payer perspective in Austria, Italy, and Spain.
BACKGROUND: This study aimed to establish a payer-perspective cost-effectiveness and budget impact model of adjustable gastric banding (AGB) and gastric bypass (GBP) vs. conventional treatment (CT) in patients with a body mass index (BMI) > or = 35 kg x m(-2) and type 2 diabetes mellitus (T2DM) in Austria, Italy, and Spain. METHODS: A health economics model described in a previous publication was applied to resource utilization and cost data in AGB, GBP, and CT from Austria, Italy, and Spain in 2009. RESULTS: The base case time scope is 5 years; the annual discount rate for utilities and costs is 3.5%. In Austria and Italy, both AGB and GBP are cost-saving and are thus dominant in terms of incremental cost-effectiveness ratio compared to CT. In Spain, AGB and GBP yield a moderate cost increase but are cost-effective, assuming a willingness-to-pay threshold of 30,000 euro per quality adjusted life-year. Under worst-case analysis, AGB and GBP remain cost-saving or around breakeven in Austria and Italy and remain cost-effective in Spain. CONCLUSION: In patients with T2DM and BMI > or = 35 kg x m(-2) at 5-year follow-up vs. CT, AGB and GBP are not only clinically effective and safe but represent satisfactory value for money from a payer perspective in Austria, Italy, and Spain.
Authors: O Moreno; A Meoro; A Martinez; C Rodriguez; C Pardo; S Aznar; P Lopez; J Serrano; E Boix; M D Martin; A M Pico Alfonso Journal: J Endocrinol Invest Date: 2006 Jul-Aug Impact factor: 4.256
Authors: Thomas Dorner; Theres Rathmanner; Monika Lechleitner; Robert Schlögel; Michael Roden; Kitty Lawrence; Franz Schwarz; Ingrid Kiefer; Michael Kunze; Anita Rieder Journal: Wien Klin Wochenschr Date: 2006-09 Impact factor: 1.704
Authors: Guido H H Mannaerts; Rowaa E A Allatif; Fatima Y Al Hashmi; Arati Bhosale; Ahmad N Hammo; Sujoud H Isied; Warda A Qureshi; Omar S Al Hamad; Yasser Kayyal; Hmouda S T Al Afari Journal: Obes Surg Date: 2019-07 Impact factor: 4.129