Literature DB >> 19756767

[Neuromodulation of spasticity in children by intrathecal baclofen].

R Cumlivski1, G Redl, W Strobl, W Girsch, A Krebs, P Machowetz.   

Abstract

INTRODUCTION: Treatment with intrathecal baclofen (ITB) is an important part of the complex therapy of patients with cerebral spasticity aiming to improve the motoric functions and to reduce pain intensity.
MATERIAL AND METHODS: ITB was started in the Orthopaedic Hospital in Speising in 1999. From 1999 to 2006 a total of 15 children aged 3 to 16 years old were selected for this special treatment.
RESULTS: The average degree of spasticity according to Ashworth (scale 1-5) could be reduced by ITB from 4.38 to 3.0, the time spent sitting could be increased from 3.3 to 5.8h per day and the pain intensity (VAS 1-10) could be reduced from 4.2 to 0.6. The time necessary for nursing treatment was shortened from 7.5 to 3.4 (VAS 1-10). Also improved was the emotional situation, the ability to swallow, the posture of the head and the concentration ability.
CONCLUSION: ITB provides neuromodulation even in pediatric patients with complex neuromotoric spasticity.

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Year:  2009        PMID: 19756767     DOI: 10.1007/s00482-009-0841-2

Source DB:  PubMed          Journal:  Schmerz        ISSN: 0932-433X            Impact factor:   1.107


  12 in total

1.  Hip status in cerebral palsy after one year of continuous intrathecal baclofen infusion.

Authors:  Linda E Krach; Robert L Kriel; Richard C Gilmartin; Dale M Swift; Bruce B Storrs; Rick Abbott; John D Ward; Karen K Bloom; William H Brooks; Joseph R Madsen; John F McLaughlin; Joseph M Nadell
Journal:  Pediatr Neurol       Date:  2004-03       Impact factor: 3.372

Review 2.  Intrathecal baclofen therapy in children.

Authors:  A Leland Albright; Susan S Ferson
Journal:  Neurosurg Focus       Date:  2006-08-15       Impact factor: 4.047

3.  Plasma baclofen levels in children receiving continuous intrathecal baclofen infusion.

Authors:  A L Albright; B L Shultz
Journal:  J Child Neurol       Date:  1999-06       Impact factor: 1.987

4.  Clinical considerations in cerebral palsy and spasticity.

Authors:  J E Brunstrom
Journal:  J Child Neurol       Date:  2001-01       Impact factor: 1.987

Review 5.  Selective posterior rhizotomy and intrathecal baclofen for the treatment of spasticity.

Authors:  C S von Koch; T S Park; P Steinbok; M Smyth; W J Peacock
Journal:  Pediatr Neurosurg       Date:  2001-08       Impact factor: 1.162

6.  Long-term intrathecal baclofen therapy for severe spasticity of cerebral origin.

Authors:  A Leland Albright; Richard Gilmartin; Dale Swift; Linda E Krach; Cindy B Ivanhoe; John F McLaughlin
Journal:  J Neurosurg       Date:  2003-02       Impact factor: 5.115

7.  Midthoracic catheter tip placement for intrathecal baclofen administration in children with quadriparetic spasticity.

Authors:  P A Grabb; S Guin-Renfroe; J M Meythaler
Journal:  Neurosurgery       Date:  1999-10       Impact factor: 4.654

8.  Intrathecal baclofen in children with spastic cerebral palsy: a double-blind, randomized, placebo-controlled, dose-finding study.

Authors:  Marjanke A Hoving; Elisabeth P M van Raak; Geert H J J Spincemaille; Liesbeth J Palmans; Frans A M Sleypen; Johan S H Vles
Journal:  Dev Med Child Neurol       Date:  2007-09       Impact factor: 5.449

9.  Intrathecal baclofen therapy in children with intractable spastic cerebral palsy: a cost-effectiveness analysis.

Authors:  M A Hoving; S M A A Evers; A J H A Ament; E P M van Raak; J S H Vles
Journal:  Dev Med Child Neurol       Date:  2008-04-14       Impact factor: 5.449

10.  Stretch reflex regulation in healthy subjects and patients with spasticity.

Authors:  Jens Bo Nielsen; Nikolaj T Petersen; Clarissa Crone; Thomas Sinkjaer
Journal:  Neuromodulation       Date:  2005-01
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