Literature DB >> 19756440

[Severe anemia and chronic alcohol abuse lacking signs of gastrointestinal bleeding in a 40-year-old].

M Tiller1, F Gundling, H Rohrbach, B Melzner, A Schneider, W Schepp.   

Abstract

We report about a 40 year old patient presenting a severe anemia caused by a folate deficiency combined with chronic alcohol abuse and probable liver cirrhosis. Besides pathophysiology and etiology of folate deficiency the correlation of malnutrition and liver cirrhosis (in particular caused by alcohol abuse) is discussed. As a conclusion for clinical practice the necessity of an extensive investigation for causes of an existing anemia, even in cases, which very much seem to be caused by an acute bleeding event, shall be demonstrated. Furthermore this report shows the importance of a consistent nutrition counseling of patients with liver cirrhosis.

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Year:  2010        PMID: 19756440     DOI: 10.1007/s00108-009-2444-5

Source DB:  PubMed          Journal:  Internist (Berl)        ISSN: 0020-9554            Impact factor:   0.743


  11 in total

1.  Glutamate carboxypeptidase II: a polymorphism associated with lower levels of serum folate and hyperhomocysteinemia.

Authors:  A M Devlin; E H Ling; J M Peerson; S Fernando; R Clarke; A D Smith; C H Halsted
Journal:  Hum Mol Genet       Date:  2000-11-22       Impact factor: 6.150

Review 2.  [Nutrition in liver cirrhosis].

Authors:  Felix Gundling; Niels Teich; Hendrik Martin Strebel; Wolfgang Schepp; Christian Pehl
Journal:  Med Klin (Munich)       Date:  2007-06-15

3.  Human intestinal folate transport: cloning, expression, and distribution of complementary RNA.

Authors:  T T Nguyen; D L Dyer; D D Dunning; S A Rubin; K E Grant; H M Said
Journal:  Gastroenterology       Date:  1997-03       Impact factor: 22.682

Review 4.  Current concepts in the diagnosis of cobalamin deficiency.

Authors:  R Green; L J Kinsella
Journal:  Neurology       Date:  1995-08       Impact factor: 9.910

Review 5.  Folate metabolism and requirements.

Authors:  L B Bailey; J F Gregory
Journal:  J Nutr       Date:  1999-04       Impact factor: 4.798

6.  [Differential diagnosis of a macrocytic, hyperchromic anemia following alcohol abuse and simultaneous therapy with triamterene and cotrimoxazole].

Authors:  C Kahl; M Freund
Journal:  Dtsch Med Wochenschr       Date:  2005-09-23       Impact factor: 0.628

Review 7.  New insights into carrier binding and epithelial uptake of the erythropoietic nutrients cobalamin and folate.

Authors:  Søren K Moestrup
Journal:  Curr Opin Hematol       Date:  2006-05       Impact factor: 3.284

8.  Analysis and biochemistry of blood folate.

Authors:  M D Lucock; I Daskalakis; C J Schorah; M I Levene; R Hartley
Journal:  Biochem Mol Med       Date:  1996-06

9.  A case of persistent anemia and alcohol abuse.

Authors:  Gemma Lewis; Matthew P Wise; Christopher Poynton; Andrew Godkin
Journal:  Nat Clin Pract Gastroenterol Hepatol       Date:  2007-09

10.  Metabolic interactions of alcohol and folate.

Authors:  Charles H Halsted; Jesus A Villanueva; Angela M Devlin; Carol J Chandler
Journal:  J Nutr       Date:  2002-08       Impact factor: 4.798

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