Literature DB >> 19756239

The Role of Inflammation in the Pathogenesis of Colorectal Cancer.

Beth B McConnell, Vincent W Yang.   

Abstract

Chronic inflammatory disorders are often associated with an increased risk of developing cancer. A classic example of the connection between inflammation and cancer is the increased risk of colorectal cancer in patients with inflammatory bowel disease (IBD). In this review, we discuss aspects of IBD that promote colorectal cancer and highlight key molecular mediators that contribute to cancer risk. Additionally, we report on progress in identifying molecular targets that may prove efficacious in blocking the progression of IBD-related inflammation to cancer.

Entities:  

Year:  2009        PMID： 19756239      PMCID： PMC2743014          DOI： 10.1007/s11888-009-0011-z

Source DB:  PubMed          Journal:  Curr Colorectal Cancer Rep        ISSN： 1556-3790


  42 in total

1.  Cyclooxygenase-2 increased the angiogenic and metastatic potential of tumor cells.

Authors:  Guoping Li; Tian Yang; Jun Yan
Journal:  Biochem Biophys Res Commun       Date:  2002-12-20       Impact factor: 3.575

2.  Secretion imbalance between tumour necrosis factor and its inhibitor in inflammatory bowel disease.

Authors:  M Noguchi; N Hiwatashi; Z Liu; T Toyota
Journal:  Gut       Date:  1998-08       Impact factor: 23.059

3.  Inhibitors of prostaglandin synthesis inhibit human prostate tumor cell invasiveness and reduce the release of matrix metalloproteinases.

Authors:  F A Attiga; P M Fernandez; A T Weeraratna; M J Manyak; S R Patierno
Journal:  Cancer Res       Date:  2000-08-15       Impact factor: 12.701

4.  Blocking TNF-alpha in mice reduces colorectal carcinogenesis associated with chronic colitis.

Authors:  Boryana K Popivanova; Kazuya Kitamura; Yu Wu; Toshikazu Kondo; Takashi Kagaya; Shiuchi Kaneko; Masanobu Oshima; Chifumi Fujii; Naofumi Mukaida
Journal:  J Clin Invest       Date:  2008-02       Impact factor: 14.808

5.  Severity of inflammation is a risk factor for colorectal neoplasia in ulcerative colitis.

Authors:  Matthew Rutter; Brian Saunders; Kay Wilkinson; Steve Rumbles; Gillian Schofield; Michael Kamm; Christopher Williams; Ashley Price; Ian Talbot; Alastair Forbes
Journal:  Gastroenterology       Date:  2004-02       Impact factor: 22.682

Review 6.  NF-kappaB and cancer-identifying targets and mechanisms.

Authors:  Willscott E Naugler; Michael Karin
Journal:  Curr Opin Genet Dev       Date:  2008-04-24       Impact factor: 5.578

7.  Histologic inflammation is a risk factor for progression to colorectal neoplasia in ulcerative colitis: a cohort study.

Authors:  Roopali Bansal Gupta; Noam Harpaz; Steven Itzkowitz; Sabera Hossain; Sierra Matula; Asher Kornbluth; Carol Bodian; Thomas Ullman
Journal:  Gastroenterology       Date:  2007-08-02       Impact factor: 22.682

8.  Regulation of spontaneous intestinal tumorigenesis through the adaptor protein MyD88.

Authors:  Seth Rakoff-Nahoum; Ruslan Medzhitov
Journal:  Science       Date:  2007-07-06       Impact factor: 47.728

9.  A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1.

Authors:  Jochen Hampe; Andre Franke; Philip Rosenstiel; Andreas Till; Markus Teuber; Klaus Huse; Mario Albrecht; Gabriele Mayr; Francisco M De La Vega; Jason Briggs; Simone Günther; Natalie J Prescott; Clive M Onnie; Robert Häsler; Bence Sipos; Ulrich R Fölsch; Thomas Lengauer; Matthias Platzer; Christopher G Mathew; Michael Krawczak; Stefan Schreiber
Journal:  Nat Genet       Date:  2006-12-31       Impact factor: 38.330

Review 10.  TNF-alpha in promotion and progression of cancer.

Authors:  Frances Balkwill
Journal:  Cancer Metastasis Rev       Date:  2006-09       Impact factor: 9.264
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  34 in total

Review 1.  The role of gut microbiota (commensal bacteria) and the mucosal barrier in the pathogenesis of inflammatory and autoimmune diseases and cancer: contribution of germ-free and gnotobiotic animal models of human diseases.

Authors:  Helena Tlaskalová-Hogenová; Renata Stěpánková; Hana Kozáková; Tomáš Hudcovic; Luca Vannucci; Ludmila Tučková; Pavel Rossmann; Tomáš Hrnčíř; Miloslav Kverka; Zuzana Zákostelská; Klára Klimešová; Jaroslava Přibylová; Jiřina Bártová; Daniel Sanchez; Petra Fundová; Dana Borovská; Dagmar Srůtková; Zdeněk Zídek; Martin Schwarzer; Pavel Drastich; David P Funda
Journal:  Cell Mol Immunol       Date:  2011-01-31       Impact factor: 11.530

2.  Integration of multiple signaling pathway activities resolves K-RAS/N-RAS mutation paradox in colon epithelial cell response to inflammatory cytokine stimulation.

Authors:  Pamela K Kreeger; Yufang Wang; Kevin M Haigis; Douglas A Lauffenburger
Journal:  Integr Biol (Camb)       Date:  2010-03-08       Impact factor: 2.192

Review 3.  Nuclear factor-erythroid 2-related factor 2 as a chemopreventive target in colorectal cancer.

Authors:  Constance Lay Lay Saw; Ah-Ng Tony Kong
Journal:  Expert Opin Ther Targets       Date:  2011-01-25       Impact factor: 6.902

Review 4.  Regulation of NF-E2-related factor 2 signaling for cancer chemoprevention: antioxidant coupled with antiinflammatory.

Authors:  Rong Hu; Constance Lay-Lay Saw; Rong Yu; Ah-Ng Tony Kong
Journal:  Antioxid Redox Signal       Date:  2010-08-17       Impact factor: 8.401

5.  Adverse Childhood Experiences among a Community of Resilient Centenarians and Seniors: Implications for a Chronic Disease Prevention Framework.

Authors:  Rhonda Spencer-Hwang; Xochitl Torres; Johanny Valladares; Marco Pasco-Rubio; Molly Dougherty; Wonha Kim
Journal:  Perm J       Date:  2018

6.  Co-existence of chronic renal failure, renal clear cell carcinoma, and Blau syndrome.

Authors:  Ipek Akil; Aykan Ozguven; Ebru Canda; Omer Yilmaz; Nalan Nese; Mine Ozkol; Sandra May; Andre Franke; Sebahattin Cirak
Journal:  Pediatr Nephrol       Date:  2010-05       Impact factor: 3.714

Review 7.  Colorectal cancer in inflammatory bowel disease: review of the evidence.

Authors:  D S Keller; A Windsor; R Cohen; M Chand
Journal:  Tech Coloproctol       Date:  2019-01-30       Impact factor: 3.781

Review 8.  Inflammation and colorectal cancer, when microbiota-host mutualism breaks.

Authors:  Marco Candela; Silvia Turroni; Elena Biagi; Franck Carbonero; Simone Rampelli; Carla Fiorentini; Patrizia Brigidi
Journal:  World J Gastroenterol       Date:  2014-01-28       Impact factor: 5.742

Review 9.  MicroRNAs: Novel immunotherapeutic targets in colorectal carcinoma.

Authors:  Xiang Li; Jing Nie; Qian Mei; Wei-Dong Han
Journal:  World J Gastroenterol       Date:  2016-06-21       Impact factor: 5.742

10.  Early detection of hepatocellular carcinoma co-occurring with hepatitis C virus infection: A mathematical model.

Authors:  Abdel-Rahman Nabawy Zekri; Amira Salah El-Din Youssef; Yasser Mabrouk Bakr; Reham Mohamed Gabr; Ola Sayed Ahmed; Mostafa Hamed Elberry; Ahmed Mahmoud Mayla; Mohamed Abouelhoda; Abeer A Bahnassy
Journal:  World J Gastroenterol       Date:  2016-04-28       Impact factor: 5.742
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