Literature DB >> 19753502

A new cytotoxic iridoid from Callicarpa nudiflora.

Wen-Li Mei1, Zhuang Han, Hai-Bin Cui, You-Xing Zhao, Yuan-Yuan Deng, Hao-Fu Dai.   

Abstract

A new iridoid, named nudifloside (1), together with three known compounds, was isolated from the EtOH extract of the aerial parts of Callicarpa nudiflora Hook. The structures were elucidated by a study of their physical and spectral data. Nudifloside (1) and the isolated known compound linearoside (2) displayed inhibitory effects towards chronic myelogenous leukaemia K562 cell line, with IC(50) values of 20.7 and 36.0 microg mL(-1), respectively.

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Year:  2010        PMID： 19753502     DOI： 10.1080/14786410802267544

Source DB:  PubMed          Journal:  Nat Prod Res        ISSN： 1478-6419            Impact factor:   2.861


  3 in total

1.  Clerodane Diterpenoids from Callicarpa hypoleucophylla and Their Anti-Inflammatory Activity.

Authors:  Yu-Chi Lin; Jue-Jun Lin; Shu-Rong Chen; Tsong-Long Hwang; Shu-Yen Fang; Michal Korinek; Ching-Yeu Chen; Yun-Sheng Lin; Tung-Ying Wu; Ming-Hong Yen; Chih-Hsin Wang; Yuan-Bin Cheng
Journal:  Molecules       Date:  2020-05-13       Impact factor: 4.411

2.  Metabolic profiling of cytotoxic metabolites from five Tabebuia species supported by molecular correlation analysis.

Authors:  Seham S El-Hawary; Rabab Mohammed; Ahmed F Tawfike; Sameh Fekry AbouZid; Marwa A Taher; Usama Ramadan Abdelmohsen; Elham Amin
Journal:  Sci Rep       Date:  2021-04-16       Impact factor: 4.379

3.  Simultaneous determination of four active components in rat plasma by ultra-high performance liquid chromatography tandem-mass spectrometry/mass spectrometry and its application to a pharmacokinetic study after oral administration of Callicarpa nudiflora extract.

Authors:  Jun Shao; Shuangcheng Ma; Dongkun Zheng; Weikang Chen; Yuehua Luo
Journal:  Pharmacogn Mag       Date:  2015 Jul-Sep       Impact factor: 1.085
  3 in total

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