Literature DB >> 19752518

Prognostic role of tumor-head volume ratio in fetal sacrococcygeal teratoma.

Edgar D Sy1, Roy A Filly, Mei-Leng Cheong, Matthew S Clifton, Raul A Cortes, Shinsuke Ohashi, Katsunari Takifuji, Denise Estefan Ventura, Erich J Grethel, Amy J Wagner, Elizabeth A Gress, Robert H Ball, Hanmin Lee, Michael R Harrison.   

Abstract

OBJECTIVE: To evaluate the ability of a tumor-head volume ratio to predict outcome and incidence of hydrops in fetuses with sacrococcygeal teratoma.
METHODS: Seventy-one sonograms were reviewed retrospectively from 28 fetuses with sacrococcygeal teratoma managed in our institution. Head volume (HV) and total tumor volume were calculated from sonograms. Amount of cystic tumor was estimated to determine solid tumor volume (STV) for the STV/HV ratio.
RESULTS: Twenty percent of sonograms with STV/HV <1 and 97.3% with STV/HV >1 were associated with 1 or more abnormal sonographic signs (p = 0.000). Overall mortality was 11/27 (41%). There was no mortality in fetuses with a ratio of <1, while 11/18 (61%) of fetuses with ratio >1 died (p = 0.003).
CONCLUSION: The STV/HV ratio may be used to identify fetuses with a high risk of a poor outcome due to high-output cardiac failure and hydrops, and may help guide management.

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Year:  2009        PMID: 19752518     DOI: 10.1159/000238113

Source DB:  PubMed          Journal:  Fetal Diagn Ther        ISSN: 1015-3837            Impact factor:   2.587


  3 in total

1.  Evaluation of prenatally diagnosed fetal sacrococcygeal teratomas: A case series of seventeen pregnancies from South-central Turkey.

Authors:  Mehmet Özsürmeli; Selim Büyükkurt; Mete Sucu; Erol Arslan; Selahattin Mısırlıoğlu; Çiğdem Akçabay; Masum Kayapınar; Süleyman Cansun Demir; İsmail Cüneyt Evrüke
Journal:  Turk J Obstet Gynecol       Date:  2020-10-02

2.  Sacrococcygeal teratoma.

Authors:  V Raveenthiran
Journal:  J Neonatal Surg       Date:  2013-04-01

3.  Factors associated with poor outcome in fetuses prenatally diagnosed with sacrococcygeal teratoma.

Authors:  Lieke J van Heurn; Audrey B C Coumans; Joep P M Derikx; Mireille N Bekker; Katia M Bilardo; Leonie K Duin; Maarten F C M Knapen; Eva Pajkrt; Esther Sikkel; L W Ernest van Heurn; Dick Oepkes
Journal:  Prenat Diagn       Date:  2021-08-05       Impact factor: 3.242

  3 in total

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