Literature DB >> 19751145

Genetic diversity of HIV type 1 along the coastal strip of Kenya.

Samoel A Khamadi1, Raphael W Lihana, Saida Osman, Joseph Mwangi, Joseph Muriuki, Nancy Lagat, Joyceline Kinyua, Matilu Mwau, Sheila Kageha, Vincent Okoth, Washington Ochieng, Fredrick A Okoth.   

Abstract

A study on the genetic diversity of HIV-1 subtypes present along the coastal strip of Kenya, i.e., Kilifi, Mombasa, Msambweni, and Malindi districts, was carried out. DNA sequences for regions encoding a portion of the env-gp41 region of the virus were generated by PCR and sequenced directly. Eighty six samples that were successfully sequenced were analyzed. From the analysis, 86% (74) were subtype A1, 5% (4) were subtype C, 8% (7) were subtype D, and 1% (1) was subtype G. This study shows that HIV-1 subtype A1 is the most dominant subtype in circulation in this region.

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Year:  2009        PMID： 19751145     DOI： 10.1089/aid.2009.0005

Source DB:  PubMed          Journal:  AIDS Res Hum Retroviruses        ISSN： 0889-2229            Impact factor:   2.205


  10 in total

1.  Genotypic Variability of HIV-1 Reverse Transcriptase Gene from Long-Term Antiretroviral-Experienced Patients in Kenya.

Authors:  Timothy J Nzomo; Rose C Kitawi; Ruth S Mwatelah; Rashid Aman; Maureen J Kimulwo; Geoffrey Masankwa; Javan Okendo; Raphael M Lwembe; Bernhards Ogutu; Anne Muigai; Washingtone Ochieng
Journal:  AIDS Res Hum Retroviruses       Date:  2015-03-31       Impact factor: 2.205

2.  Prevalence of Transmitted Drug Resistance Mutations in HIV-1-Infected Drug-Naive Patients from Urban and Suburban Regions of Kenya.

Authors:  Simon Onsongo; Syed Hani Abidi; Samoel Khamadi; Reena Shah; Sheila Kageha; Peter Ojwang; Syed Ali; Nancy Okinda
Journal:  AIDS Res Hum Retroviruses       Date:  2015-09-24       Impact factor: 2.205

3.  Older age at infection and nulliparity are associated with long-term non-progression in female sex workers infected with non-subtype B HIV-1.

Authors:  Vernon Mochache; Barbra A Richardson; Linnet N Masese; Susan M Graham; Kishorchandra Mandaliya; John Kinuthia; Walter Jaoko; Julie Overbaugh; R Scott McClelland
Journal:  Int J STD AIDS       Date:  2020-04-15       Impact factor: 1.359

4.  HIV type 1 in a rural coastal town in Kenya shows multiple introductions with many subtypes and much recombination.

Authors:  Stéphane Hué; Amin S Hassan; Helen Nabwera; Eduard J Sanders; Deenan Pillay; James A Berkley; Patricia A Cane
Journal:  AIDS Res Hum Retroviruses       Date:  2011-07-19       Impact factor: 2.205

5.  HIV diversity and drug resistance from plasma and non-plasma analytes in a large treatment programme in western Kenya.

Authors:  Rami Kantor; Allison DeLong; Maya Balamane; Leeann Schreier; Robert M Lloyd; Wilfred Injera; Lydia Kamle; Fidelis Mambo; Sarah Muyonga; David Katzenstein; Joseph Hogan; Nathan Buziba; Lameck Diero
Journal:  J Int AIDS Soc       Date:  2014-11-18       Impact factor: 5.396

6.  Molecular Epidemiology and Transmission Dynamics of Recent and Long-Term HIV-1 Infections in Rural Western Kenya.

Authors:  Clement Zeh; Seth C Inzaule; Pascale Ondoa; Lillian G Nafisa; Alex Kasembeli; Fredrick Otieno; Hilde Vandenhoudt; Pauli N Amornkul; Lisa A Mills; John N Nkengasong
Journal:  PLoS One       Date:  2016-02-12       Impact factor: 3.240

7.  Partial HIV C2V3 envelope sequence analysis reveals association of coreceptor tropism, envelope glycosylation and viral genotypic variability among Kenyan patients on HAART.

Authors:  Rose C Kitawi; Carol W Hunja; Rashid Aman; Bernhards R Ogutu; Anne W T Muigai; Gilbert O Kokwaro; Washingtone Ochieng
Journal:  Virol J       Date:  2017-02-14       Impact factor: 4.099

8.  HIV-1 subtype diversity, transmission networks and transmitted drug resistance amongst acute and early infected MSM populations from Coastal Kenya.

Authors:  Amin S Hassan; Joakim Esbjörnsson; Elizabeth Wahome; Alexander Thiong'o; George N Makau; Mathew A Price; Eduard J Sanders
Journal:  PLoS One       Date:  2018-12-18       Impact factor: 3.240

9.  HIV-1 Transmission Patterns Within and Between Risk Groups in Coastal Kenya.

Authors:  Joakim Esbjörnsson; Eduard J Sanders; George M Nduva; Amin S Hassan; Jamirah Nazziwa; Susan M Graham
Journal:  Sci Rep       Date:  2020-04-21       Impact factor: 4.379

10.  Phylodynamics of HIV-1 subtype C epidemic in east Africa.

Authors:  Edson Oliveira Delatorre; Gonzalo Bello
Journal:  PLoS One       Date:  2012-07-27       Impact factor: 3.240
  10 in total

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