| Literature DB >> 19748462 |
Mario Fabri1, Robert L Modlin.
Abstract
Recent discoveries have revealed the importance of the vitamin D-dependent generation of antimicrobial peptides in human host defense against Mycobacterium tuberculosis. Now, Yuk et al. (2009) show how vitamin D induces autophagy and mediates colocalization of Mycobacterium tuberculosis and antimicrobial peptides within an autophagolysosome, leading to killing of the bacterium.Entities:
Mesh:
Substances:
Year: 2009 PMID: 19748462 DOI: 10.1016/j.chom.2009.08.008
Source DB: PubMed Journal: Cell Host Microbe ISSN: 1931-3128 Impact factor: 21.023