Literature DB >> 19748460

Making sense of antisense in antibiotic drug discovery.

Gerard D Wright1.   

Abstract

In an era of increasing antibiotic resistance, growing clinical need for new drugs, and few lead molecules, new research is helping to identify new targets and the mechanism of action of lead molecules.

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Year:  2009        PMID: 19748460     DOI: 10.1016/j.chom.2009.08.009

Source DB:  PubMed          Journal:  Cell Host Microbe        ISSN: 1931-3128            Impact factor:   21.023


  5 in total

Review 1.  Ecology and evolution as targets: the need for novel eco-evo drugs and strategies to fight antibiotic resistance.

Authors:  Fernando Baquero; Teresa M Coque; Fernando de la Cruz
Journal:  Antimicrob Agents Chemother       Date:  2011-05-16       Impact factor: 5.191

2.  Comparison of microplate and macrodilution methods in time-kill study of new antimicrobial drugs.

Authors:  Ying Zhou; Zheng Hou; Chao Fang; Xiaoyan Xue; Fei Da; Yukun Wang; Hui Bai; Xiaoxing Luo
Journal:  Folia Microbiol (Praha)       Date:  2012-06-09       Impact factor: 2.099

3.  Antisense growth inhibition of methicillin-resistant Staphylococcus aureus by locked nucleic acid conjugated with cell-penetrating peptide as a novel FtsZ inhibitor.

Authors:  Jingru Meng; Fei Da; Xue Ma; Ning Wang; Yukun Wang; Huinan Zhang; Mingkai Li; Ying Zhou; Xiaoyan Xue; Zheng Hou; Min Jia; Xiaoxing Luo
Journal:  Antimicrob Agents Chemother       Date:  2014-11-24       Impact factor: 5.191

4.  Targeting RNA polymerase primary σ70 as a therapeutic strategy against methicillin-resistant Staphylococcus aureus by antisense peptide nucleic acid.

Authors:  Hui Bai; Guojun Sang; Yu You; Xiaoyan Xue; Ying Zhou; Zheng Hou; Jingru Meng; Xiaoxing Luo
Journal:  PLoS One       Date:  2012-01-10       Impact factor: 3.240

Review 5.  Breaking the Spell: Combating Multidrug Resistant 'Superbugs'.

Authors:  Shahper N Khan; Asad U Khan
Journal:  Front Microbiol       Date:  2016-02-18       Impact factor: 5.640

  5 in total

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