| Literature DB >> 19748431 |
Carlos Hernan Rodriguez1, Rodriguez Carlos Hernan, Karina Bombicino, Bombicino Karina, Gabriela Granados, Granados Gabriela, Marcela Nastro, Nastro Marcela, Carlos Vay, Vay Carlos, Angela Famiglietti, Famiglietti Angela.
Abstract
Colistin heteroresistance in Acinetobacter baumannii (Ab) has been reported, but the clinical impact and the antimicrobial treatment have not been established yet. We observed the selection intratreatment with colistin of Ab colistin-resistant strains from a colistin-heteroresistant isolate in one patient with postneurosurgical meningitis. The presence and the genetic relationship of heteroresistant Ab isolates from intensive care units (ICUs) obtained in the same period of the case report were analyzed. Twenty-eight isolates from patients admitted to the ICUs of an Argentinian university hospital during June to December 2004 were evaluated. Genomoespecie was determined by amplified ribosomal DNA restriction analysis, and genetic similarity among the strains was determined by pulsed-field electrophoresis. Colistin heteroresistance was observed in 46, 4% of these isolates. The majority belonged to clones previously identified as I and III.Entities:
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Year: 2009 PMID： 19748431 DOI： 10.1016/j.diagmicrobio.2009.05.019
Source DB: PubMed Journal: Diagn Microbiol Infect Dis ISSN： 0732-8893 Impact factor: 2.803