| Literature DB >> 19748256 |
O N Pozharitskaya1, A N Shikov, M N Makarova, V M Kosman, N M Faustova, S V Tesakova, V G Makarov, B Galambosi.
Abstract
The anti-inflammatory potential of three doses of an aqueous infusion of aerial parts Bidens tripartita L. against carrageenan-induced acute paw edema in rats was investigated. A phytochemical study and qualitative-quantitative analyses revealed the presence of flavonoids, tannins, polysaccharides, phenols, amino acids, ascorbic acid, organic acids and polyacetylenes. Infusion doses of 20ml/kgbody wt. exhibited significant anti-inflammatory activity in rats, as compared with indomethacin. In addition, the infusion showed analgesic properties in a hot-plate test and antipyretic properties in carrageenan-induced local hyperthermia, both in rats. The effects were dose-dependent. Our results provide evidence for the potential usefulness of B. tripartita infusion in the treatment of inflammatory disorders. Copyright 2009 Elsevier GmbH. All rights reserved.Entities:
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Year: 2009 PMID： 19748256 DOI： 10.1016/j.phymed.2009.08.001
Source DB: PubMed Journal: Phytomedicine ISSN： 0944-7113 Impact factor: 5.340