Junaid Patel1, Mary N Sheppard. 1. CRY Centre for Cardiac Pathology, National Heart and Lung Institute, Imperial College, London, UK. junaid.patel@ic.ac.uk
Abstract
BACKGROUND: Primary cardiac and pericardial tumours are rare with a prevalence of between 0.001% and 0.3%. Thus, general pathologists are not familiar with them. Modern advances in cardiac imaging have increased the number of patients identified with a primary cardiac tumour in its early stage and also improved prognosis. At the Royal Brompton Hospital, London, we did a retrospective study to investigate the pathological features of primary cardiac and pericardial tumours and compared our findings to other cardiac centres. METHODS: All pathologic records at the Royal Brompton Hospital between 1990 and 2008 were reviewed to identify patients with a confirmed diagnosis of primary cardiac tumours. A total of 94 patients with a histological diagnosis of primary cardiac and pericardial tumours were identified and formed the study population. RESULTS: The majority (n=67, 71.3%) of cases were benign cardiac tumours. Myxoma was the most common histologic type accounting for 27 cases. Among cases with primary malignant tumours (n=27, 28.7%), unclassified sarcoma (n=11), leiomyosarcoma (n=5), and lymphoma (n=4) were the most common histologic types. CONCLUSION: This study, primarily from an adult setting (n=78, 83%) demonstrates a large spectrum of cardiac tumours seen in recent cardiologic practice. Myxoma is still the most common tumour but more fibroelastomas are being diagnosed due to increased imaging.
BACKGROUND: Primary cardiac and pericardial tumours are rare with a prevalence of between 0.001% and 0.3%. Thus, general pathologists are not familiar with them. Modern advances in cardiac imaging have increased the number of patients identified with a primary cardiac tumour in its early stage and also improved prognosis. At the Royal Brompton Hospital, London, we did a retrospective study to investigate the pathological features of primary cardiac and pericardial tumours and compared our findings to other cardiac centres. METHODS: All pathologic records at the Royal Brompton Hospital between 1990 and 2008 were reviewed to identify patients with a confirmed diagnosis of primary cardiac tumours. A total of 94 patients with a histological diagnosis of primary cardiac and pericardial tumours were identified and formed the study population. RESULTS: The majority (n=67, 71.3%) of cases were benign cardiac tumours. Myxoma was the most common histologic type accounting for 27 cases. Among cases with primary malignant tumours (n=27, 28.7%), unclassified sarcoma (n=11), leiomyosarcoma (n=5), and lymphoma (n=4) were the most common histologic types. CONCLUSION: This study, primarily from an adult setting (n=78, 83%) demonstrates a large spectrum of cardiac tumours seen in recent cardiologic practice. Myxoma is still the most common tumour but more fibroelastomas are being diagnosed due to increased imaging.
Authors: U Lotze; J Reponova; G Muth; G Oltmanns; H-C Reich; G Etzrodt; W A Kaiser; O Mutschke; M Ortmann; D Stippel; T Wahlers Journal: Herz Date: 2012-03-21 Impact factor: 1.443
Authors: Victoria L Martucci; Abbas Emaminia; Jaydira del Rivero; Ronald M Lechan; Bindiya T Magoon; Analyza Galia; Tito Fojo; Steve Leung; Roberto Lorusso; Camilo Jimenez; Barry L Shulkin; Jennifer L Audibert; Karen T Adams; Douglas R Rosing; Anand Vaidya; Robert G Dluhy; Keith A Horvath; Karel Pacak Journal: Am J Cardiol Date: 2015-03-24 Impact factor: 2.778