Literature DB >> 19746379

Potent and selective inhibition of acid sphingomyelinase by bisphosphonates.

Anke G Roth1, Daniela Drescher, Yang Yang, Susanne Redmer, Stefan Uhlig, Christoph Arenz.   

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Year:  2009        PMID： 19746379     DOI： 10.1002/anie.200903288

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


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  25 in total

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Review 2.  Drug targeting of sphingolipid metabolism: sphingomyelinases and ceramidases.

Authors:  Daniel Canals; David M Perry; Russell W Jenkins; Yusuf A Hannun
Journal:  Br J Pharmacol       Date:  2011-06       Impact factor: 8.739

3.  1-(Fluoroalkylidene)-1,1-bisphosphonic acids are potent and selective inhibitors of the enzymatic activity of Toxoplasma gondii farnesyl pyrophosphate synthase.

Authors:  Sergio H Szajnman; Valeria S Rosso; Leena Malayil; Alyssa Smith; Silvia N J Moreno; Roberto Docampo; Juan B Rodriguez
Journal:  Org Biomol Chem       Date:  2012-01-03       Impact factor: 3.876

4.  Acid sphingomyelinase promotes mitochondrial dysfunction due to glutamate-induced regulated necrosis.

Authors:  Sergei A Novgorodov; Joshua R Voltin; Monika A Gooz; Li Li; John J Lemasters; Tatyana I Gudz
Journal:  J Lipid Res       Date:  2017-12-27       Impact factor: 5.922

Review 5.  Small Molecule Inhibitors Targeting Biosynthesis of Ceramide, the Central Hub of the Sphingolipid Network.

Authors:  Jan Skácel; Barbara S Slusher; Takashi Tsukamoto
Journal:  J Med Chem       Date:  2021-01-04       Impact factor: 7.446

6.  Potent inhibition of Acid ceramidase by novel B-13 analogues.

Authors:  Denny Proksch; Jan Jasper Klein; Christoph Arenz
Journal:  J Lipids       Date:  2010-12-09

7.  Design, synthesis and biological evaluation of sulfur-containing 1,1-bisphosphonic acids as antiparasitic agents.

Authors:  Marion Recher; Alejandro P Barboza; Zhu-Hong Li; Melina Galizzi; Mariana Ferrer-Casal; Sergio H Szajnman; Roberto Docampo; Silvia N J Moreno; Juan B Rodriguez
Journal:  Eur J Med Chem       Date:  2012-12-20       Impact factor: 6.514

8.  Acid sphingomyelinase deficiency protects mitochondria and improves function recovery after brain injury.

Authors:  Sergei A Novgorodov; Joshua R Voltin; Wenxue Wang; Stephen Tomlinson; Christopher L Riley; Tatyana I Gudz
Journal:  J Lipid Res       Date:  2019-01-20       Impact factor: 5.922

9.  Ceramide sphingolipid signaling mediates Tumor Necrosis Factor (TNF)-dependent toxicity via caspase signaling in dopaminergic neurons.

Authors:  Terina N Martinez; Xi Chen; Sibali Bandyopadhyay; Alfred H Merrill; Malú G Tansey
Journal:  Mol Neurodegener       Date:  2012-09-13       Impact factor: 14.195

10.  Pulsatile ex vivo perfusion of human saphenous vein grafts under controlled pressure conditions increases MMP-2 expression.

Authors:  Sara Dummler; Stefan Eichhorn; Christian Tesche; Ulrich Schreiber; Bernhard Voss; Marcus-André Deutsch; Hans Hauner; Harald Lahm; Rüdiger Lange; Markus Krane
Journal:  Biomed Eng Online       Date:  2011-07-21       Impact factor: 2.819
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