Literature DB >> 19746328

[Ears "made of stone" - unusual secondary phenomenon of undersubstituted adrenal insufficiency].

Jens Christian Richter1, B Chappuis.   

Abstract

HISTORY AND CLINICAL
FINDINGS: A 69-year-old man was admitted with cough, fever and dyspnea. For years, an adrenal insufficiency has been substituted with low-dose hydrocortisone. The hypotensive and tachycardic patient exhibited remarkable stony hard ears. INVESTIGATIONS: Elevated inflammatory markers and the clinical picture point to a pulmonary focus of infection. Radiographs of the ears show trabecular structures as a sign of true ossification. DIAGNOSIS, TREATMENT AND COURSE: Addisonian crisis due to pulmonary infection was treated successfully with steroids, antibiotics and intravenous fluids. The auricular ossification was interpreted as a secondary phenomenon of undersubstituted adrenal insufficiency.
CONCLUSION: Adrenal insufficiency should be considered when auricular ossification is encountered. The pathogenesis of this phenomenon is complex and not well understood. Georg Thieme Verlag KG Stuttgart * New York.

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Year:  2009        PMID: 19746328     DOI: 10.1055/s-0029-1237526

Source DB:  PubMed          Journal:  Dtsch Med Wochenschr        ISSN: 0012-0472            Impact factor:   0.628


  2 in total

Review 1.  Role of proopiomelanocortin-derived peptides and their receptors in the osteoarticular system: from basic to translational research.

Authors:  Markus Böhm; Susanne Grässel
Journal:  Endocr Rev       Date:  2012-06-26       Impact factor: 19.871

2.  Adrenal insufficiency presenting as bilateral rigid auricles: a case report.

Authors:  Mark Vincent Koning; Ard Struijs
Journal:  J Med Case Rep       Date:  2014-09-10
  2 in total

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