Literature DB >> 19744832

Neurocognitive diagnosis and cut-off scores of the Screen for Cognitive Impairment in Psychiatry (SCIP-S).

Emilio Rojo1, Oscar Pino, Georgina Guilera, Juana Gómez-Benito, Scot E Purdon, Benedicto Crespo-Facorro, Manuel J Cuesta, Manuel Franco, Anabel Martínez-Arán, Nuria Segarra, Rafael Tabarés-Seisdedos, Eduard Vieta, Miguel Bernardo, Francisco Mesa, Javier Rejas.   

Abstract

OBJECTIVES: To demonstrate the ability of the Screen for Cognitive Impairment in Psychiatry (SCIP-S) to discriminate between cognitively-impaired individuals and those with adequate functioning in a sample of schizophrenic and bipolar patients, as well as in a control group.
METHODS: The SCIP-S, together with a full neuropsychological battery, was administered to three groups: patients with schizophrenia, patients diagnosed with bipolar disorder I, and controls. The battery scores were used to perform a standardization with respect to the control group and this served to determine the comparison groups (cognitively impaired versus unimpaired) for each of the subtests of the SCIP-S. A full analysis of decision validity was conducted on the basis of receiver operating characteristic curves (sensitivity and specificity, +LR and -LR, PPV and NPV).
RESULTS: All the subtests yielded adequate values for sensitivity and specificity with the proposed cut-off points, while the total score of the SCIP (<70) was associated with a sensitivity of 87.9 and specificity of 80.6.
CONCLUSIONS: The SCIP-S shows adequate decision validity as a screening tool for cognitive deficit in patients diagnosed with schizophrenia or bipolar disorder. 2009 Elsevier B.V. All rights reserved.

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Year:  2009        PMID: 19744832     DOI: 10.1016/j.schres.2009.08.005

Source DB:  PubMed          Journal:  Schizophr Res        ISSN: 0920-9964            Impact factor:   4.939


  15 in total

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