A 58 year old woman with a corpus callosum nodule at autopsy.

Intracranial lipomas are uncommon benign mesenchymal tumors, found usually near or at the midline. The existence of such intracranial tumors has been documented in the literature in only over 200 cases. Although usually asymptomatic, they can sometimes trigger neurological symptoms, specifically epileptic seizures. We describe the incidental finding of a lipoma of the corpus callosum at autopsy in a 58 year-old woman with a history of seizures, and provide a concise review of the pertinent literature with respect to this entity.