Literature DB >> 19743809

Bioactive guanidine alkaloids from two Caribbean marine sponges.

Rémi Laville1, Olivier P Thomas, Fabrice Berrué, Diana Marquez, Jean Vacelet, Philippe Amade.   

Abstract

Seven new guanidine alkaloids (1-7) together with the known batzelladines A, F, H, and L, ptilomycalin A, and fromiamycalin were isolated from the Caribbean marine sponges Monanchora arbuscula and Clathria calla. Molecular structures were assigned on the basis of detailed analysis of 1D and 2D NMR spectra and mass spectrometry data, and bioactivities of the alkaloids were evaluated against human cancer cell lines and malaria protozoa.

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Year:  2009        PMID: 19743809     DOI: 10.1021/np900244g

Source DB:  PubMed          Journal:  J Nat Prod        ISSN: 0163-3864            Impact factor:   4.050


  21 in total

1.  Syntheses of Cyclic Guanidine-Containing Natural Products.

Authors:  Yuyong Ma; Saptarshi De; Chuo Chen
Journal:  Tetrahedron       Date:  2015-02-25       Impact factor: 2.457

2.  Desymmetrization of meso-2,5-diallylpyrrolidinyl ureas through asymmetric palladium-catalyzed carboamination: stereocontrolled synthesis of bicyclic ureas.

Authors:  Nicholas R Babij; John P Wolfe
Journal:  Angew Chem Int Ed Engl       Date:  2013-07-03       Impact factor: 15.336

3.  A convergent approach to batzelladine alkaloids. Total syntheses of (+)-batzelladine E, (-)-dehydrobatzelladine C, and (+)-batzelladine K.

Authors:  Christos Economou; Justin P Romaire; Tony Z Scott; Brendan T Parr; Seth B Herzon
Journal:  Tetrahedron       Date:  2018-04-18       Impact factor: 2.457

4.  Bis(N-amidinohydrazones) and N-(amidino)-N'-aryl-bishydrazones: New classes of antibacterial/antifungal agents.

Authors:  Sanjib K Shrestha; Liliia M Kril; Keith D Green; Stefan Kwiatkowski; Vitaliy M Sviripa; Justin R Nickell; Linda P Dwoskin; David S Watt; Sylvie Garneau-Tsodikova
Journal:  Bioorg Med Chem       Date:  2016-10-10       Impact factor: 3.641

5.  Araiosamines A-D: tris-bromoindole cyclic guanidine alkaloids from the marine sponge Clathria (Thalysias) araiosa.

Authors:  Xiaomei Wei; Niel M Henriksen; Jack J Skalicky; Mary Kay Harper; Thomas E Cheatham; Chris M Ireland; Ryan M Van Wagoner
Journal:  J Org Chem       Date:  2011-04-11       Impact factor: 4.354

Review 6.  The structural diversity and promise of antiparasitic marine invertebrate-derived small molecules.

Authors:  Katharine R Watts; Karen Tenney; Phillip Crews
Journal:  Curr Opin Biotechnol       Date:  2010-10-16       Impact factor: 9.740

7.  Concise Synthesis and Antimicrobial Evaluation of the Guanidinium Alkaloid Batzelladine D: Development of a Stereodivergent Strategy.

Authors:  You-Chen Lin; Aubert Ribaucourt; Yasamin Moazami; Joshua G Pierce
Journal:  J Am Chem Soc       Date:  2020-05-12       Impact factor: 15.419

8.  Stereocontrolled synthesis of bicyclic ureas and sulfamides via Pd-catalyzed alkene carboamination reactions.

Authors:  Nicholas R Babij; Jordan R Boothe; Grace M McKenna; Ryan M Fornwald; John P Wolfe
Journal:  Tetrahedron       Date:  2019-04-20       Impact factor: 2.457

9.  A concise synthesis of (+)-batzelladine B from simple pyrrole-based starting materials.

Authors:  Brendan T Parr; Christos Economou; Seth B Herzon
Journal:  Nature       Date:  2015-09-16       Impact factor: 49.962

10.  Crambescin C1 Exerts a Cytoprotective Effect on HepG2 Cells through Metallothionein Induction.

Authors:  María Roel; Juan A Rubiolo; Eva Ternon; Olivier P Thomas; Mercedes R Vieytes; Luis M Botana
Journal:  Mar Drugs       Date:  2015-07-27       Impact factor: 5.118

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