Literature DB >> 1974368

How the messenger got its tail: addition of poly(A) in the nucleus.

M Wickens1.   

Abstract

Most mRNAs end in a poly(A) tail, the addition of which is catalysed by a poly(A) polymerase in conjunction with a distinct factor that provides specificity for mRNAs. The reaction is dynamic, involving separable initiation, elongation and termination phases. A companion article in next month's TIBS will review the regulation of poly(A) addition and removal during early animal development.

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Year:  1990        PMID: 1974368     DOI: 10.1016/0968-0004(90)90054-f

Source DB:  PubMed          Journal:  Trends Biochem Sci        ISSN: 0968-0004            Impact factor:   13.807


  132 in total

1.  Utilization of splicing elements and polyadenylation signal elements in the coupling of polyadenylation and last-intron removal.

Authors:  C Cooke; H Hans; J C Alwine
Journal:  Mol Cell Biol       Date:  1999-07       Impact factor: 4.272

2.  Functionally significant secondary structure of the simian virus 40 late polyadenylation signal.

Authors:  H Hans; J C Alwine
Journal:  Mol Cell Biol       Date:  2000-04       Impact factor: 4.272

Review 3.  Formation of mRNA 3' ends in eukaryotes: mechanism, regulation, and interrelationships with other steps in mRNA synthesis.

Authors:  J Zhao; L Hyman; C Moore
Journal:  Microbiol Mol Biol Rev       Date:  1999-06       Impact factor: 11.056

4.  Map of cis-acting sequences that determine alternative pre-mRNA processing in the E3 complex transcription unit of adenovirus.

Authors:  H A Brady; A Scaria; W S Wold
Journal:  J Virol       Date:  1992-10       Impact factor: 5.103

5.  Separation of factors required for cleavage and polyadenylation of yeast pre-mRNA.

Authors:  J Chen; C Moore
Journal:  Mol Cell Biol       Date:  1992-08       Impact factor: 4.272

6.  Several distinct types of sequence elements are required for efficient mRNA 3' end formation in a pea rbcS gene.

Authors:  B D Mogen; M H MacDonald; G Leggewie; A G Hunt
Journal:  Mol Cell Biol       Date:  1992-12       Impact factor: 4.272

7.  Cloning and characterization of the Drosophila homolog of the xeroderma pigmentosum complementation-group B correcting gene, ERCC3.

Authors:  M H Koken; C Vreeken; S A Bol; N C Cheng; I Jaspers-Dekker; J H Hoeijmakers; J C Eeken; G Weeda; A Pastink
Journal:  Nucleic Acids Res       Date:  1992-11-11       Impact factor: 16.971

8.  Site-specific RNA cleavage generates the 3' end of a poxvirus late mRNA.

Authors:  J B Antczak; D D Patel; C A Ray; B S Ink; D J Pickup
Journal:  Proc Natl Acad Sci U S A       Date:  1992-12-15       Impact factor: 11.205

9.  The upstream sequence element of the C2 complement poly(A) signal activates mRNA 3' end formation by two distinct mechanisms.

Authors:  A Moreira; Y Takagaki; S Brackenridge; M Wollerton; J L Manley; N J Proudfoot
Journal:  Genes Dev       Date:  1998-08-15       Impact factor: 11.361

10.  Sequences homologous to 5' splice sites are required for the inhibitory activity of papillomavirus late 3' untranslated regions.

Authors:  P A Furth; W T Choe; J H Rex; J C Byrne; C C Baker
Journal:  Mol Cell Biol       Date:  1994-08       Impact factor: 4.272

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