Literature DB >> 19742252

Thrombotic thrombocytopenic purpura and systemic lupus erythematosus: successful management of a rare presentation.

Pratish George1, Jasmine Das, Basant Pawar, Naveen Kakkar.   

Abstract

Thrombotic thrombocytopenic purpura (TTP) and systemic lupus erythematosus (SLE) very rarely present simultaneously and pose a diagnostic and therapeutic dilemma to the critical care team. Prompt diagnosis and management with plasma exchange and immunosuppression is life-saving. A patient critically ill with TTP and SLE, successfully managed in the acute period of illness with plasma exchange, steroids and mycophenolate mofetil is described.

Entities:  

Keywords:  Plasma exchange; systemic lupus erythematosus; thrombotic thrombocytopenic purpura

Year:  2008        PMID： 19742252      PMCID： PMC2738311          DOI： 10.4103/0972-5229.43682

Source DB:  PubMed          Journal:  Indian J Crit Care Med        ISSN： 0972-5229


  18 in total

1.  Complications of plasma exchange in thrombotic thrombocytopenic purpura-hemolytic uremic syndrome: a study of 78 additional patients.

Authors:  J R McMinn; Ira A Thomas; Deirdra R Terrell; Deanna Duvall; Sara K Vesely; James N George
Journal:  Transfusion       Date:  2003-03       Impact factor: 3.157

2.  Guidelines on the diagnosis and management of the thrombotic microangiopathic haemolytic anaemias.

Authors:  Sarah L Allford; Beverley J Hunt; Peter Rose; Samuel J Machin
Journal:  Br J Haematol       Date:  2003-02       Impact factor: 6.998

3.  Frequency and significance of schistocytes in TTP/HUS patients at the discontinuation of plasma exchange therapy.

Authors:  Jennifer A Egan; Shauna N Hay; Mark E Brecher
Journal:  J Clin Apher       Date:  2004       Impact factor: 2.821

4.  The incidence of thrombotic thrombocytopenic purpura-hemolytic uremic syndrome: all patients, idiopathic patients, and patients with severe ADAMTS-13 deficiency.

Authors:  D R Terrell; L A Williams; S K Vesely; B Lämmle; J A K Hovinga; J N George
Journal:  J Thromb Haemost       Date:  2005-07       Impact factor: 5.824

5.  Outcome of severe adult thrombotic microangiopathies in the intensive care unit.

Authors:  Frédéric Pene; Cécile Vigneau; Marc Auburtin; Delphine Moreau; Jean-Ralph Zahar; Joël Coste; Farhad Heshmati; Jean-Paul Mira
Journal:  Intensive Care Med       Date:  2004-12-03       Impact factor: 17.440

6.  Plasmapheresis does not increase the risk for infection in immunosuppressed patients with severe lupus nephritis. The Lupus Nephritis Collaborative Study Group.

Authors:  M A Pohl; S P Lan; T Berl
Journal:  Ann Intern Med       Date:  1991-06-01       Impact factor: 25.391

Review 7.  Review of thrombotic thrombocytopenic purpura in the setting of systemic lupus erythematosus.

Authors:  F Musio; E M Bohen; C M Yuan; P G Welch
Journal:  Semin Arthritis Rheum       Date:  1998-08       Impact factor: 5.532

Review 8.  [Role of the biologist in the study of schistocytes].

Authors:  J F Lesesve; O Fenneteau; T Cynober; T Lecompte; M J Grange; G Flandrin; X Troussard
Journal:  Ann Biol Clin (Paris)       Date:  2003 Sep-Oct       Impact factor: 0.459

Review 9.  Thrombotic microangiopathies in the 1980s: clinical features, response to treatment, and the impact of the human immunodeficiency virus epidemic.

Authors:  C E Thompson; L E Damon; C A Ries; C A Linker
Journal:  Blood       Date:  1992-10-15       Impact factor: 22.113

10.  Morphologic diagnosis of thrombotic thrombocytopenic purpura.

Authors:  Edward R Burns; Yenmay Lou; Anjali Pathak
Journal:  Am J Hematol       Date:  2004-01       Impact factor: 10.047
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  3 in total

1.  Lupus-associated thrombotic thrombocytopenic purpura-like microangiopathy.

Authors:  Daniel Blum; Geoffrey Blake
Journal:  World J Nephrol       Date:  2015-11-06

2.  Thrombotic thrombocytopenic purpura and deep vein thrombosis as the presenting manifestations of systemic lupus erythematosus: A case report and review of literature.

Authors:  Mohammad Ali Mashhadi; Zohreh Bari
Journal:  J Res Med Sci       Date:  2011-08       Impact factor: 1.852

Review 3.  Management of acquired, immune thrombocytopenic purpura (iTTP): beyond the acute phase.

Authors:  John Paul Westwood; Marie Scully
Journal:  Ther Adv Hematol       Date:  2022-07-26
  3 in total

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