Literature DB >> 19742097

Chloroma of the forearm: a case report of leukemia recurrence presenting with compression neuropathy and tenosynovitis.

Bryan Warme1, Jaron Sullivan, Dean-Yar Tigrani, Dietz M D Fred.   

Abstract

Acute Myelogenous Leukemia (AML) typically involves intramedullary proliferation of myeloid precursor cells. Extramedullary manifestations of AML are exceedingly rare, but do occur. Granu-locytic sarcoma, or chloroma, is one example of extramedullary leukemia cells forming a tumorous mass. We report a case of Chloroma in the volar forearm compartment presenting with both median nerve compressive neuropathy and apparent tenosynovitis. Abscess was at the top of the early differential, and the patient was scheduled for operative debridement. However, further evaluation indicated that chloroma was present, thus obviating the need for emergent surgical intervention and necessitating the induction of chemotherapy. To our knowledge this is the first report of chloroma in this location and with these presenting symptoms.

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Year:  2009        PMID: 19742097      PMCID: PMC2723704     

Source DB:  PubMed          Journal:  Iowa Orthop J        ISSN: 1541-5457


  7 in total

1.  The chemistry of experimental chloroma I. Porphyrins and peroxidases.

Authors:  J SCHULTZ; H SHAY; M GRUENSTEIN
Journal:  Cancer Res       Date:  1954-03       Impact factor: 12.701

2.  Granulocytic sarcoma is associated with the 8;21 translocation in acute myeloid leukemia.

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Journal:  J Clin Oncol       Date:  1993-04       Impact factor: 44.544

3.  High risk subgroup of acute myelomonocytic leukemia (AMML) with orbito-ocular granulocytic sarcoma (OOGS) in Turkish children. Retrospective analysis of clinical, hematological, ultrastructural and therapeutical findings of thirty-three OOGS.

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Journal:  Acta Haematol       Date:  1989       Impact factor: 2.195

4.  Leukemia cutis. Analysis of 50 biopsy-proven cases with an emphasis on occurrence in myelodysplastic syndromes.

Authors:  T A Longacre; B R Smoller
Journal:  Am J Clin Pathol       Date:  1993-09       Impact factor: 2.493

Review 5.  Extramedullary myeloid cell tumors in acute nonlymphocytic leukemia: a clinical review.

Authors:  J C Byrd; W J Edenfield; D J Shields; N A Dawson
Journal:  J Clin Oncol       Date:  1995-07       Impact factor: 44.544

Review 6.  Recurrent granulocytic sarcoma. An unusual variation of acute myelogenous leukemia associated with 8;21 chromosomal translocation and blast expression of the neural cell adhesion molecule.

Authors:  J C Byrd; R B Weiss
Journal:  Cancer       Date:  1994-04-15       Impact factor: 6.860

7.  Granulocytic sarcoma in childhood leukemia: imaging features.

Authors:  M H Pui; B D Fletcher; J W Langston
Journal:  Radiology       Date:  1994-03       Impact factor: 11.105

  7 in total
  5 in total

Review 1.  Is acute myeloid leukemia a liquid tumor?

Authors:  Maro Ohanian; Stefan Faderl; Farhad Ravandi; Naveen Pemmaraju; Guillermo Garcia-Manero; Jorge Cortes; Zeev Estrov
Journal:  Int J Cancer       Date:  2013-02-04       Impact factor: 7.396

2.  Tumefactive appearance of peripheral nerve involvement in hematologic malignancies: a new imaging association.

Authors:  Stepan Capek; Marie-Noëlle Hébert-Blouin; Ross C Puffer; Carlo Martinoli; Matthew A Frick; Kimberly K Amrami; Robert J Spinner
Journal:  Skeletal Radiol       Date:  2015-04-29       Impact factor: 2.199

Review 3.  Neoplastic nerve lesions.

Authors:  Deep K Patel; Kelly G Gwathmey
Journal:  Neurol Sci       Date:  2022-02-23       Impact factor: 3.830

4.  Skeletal Muscle Lymphoma Presenting with Chronic Compartment Syndrome of Leg after Trauma.

Authors:  Jhong-You Li; Chung-Liang Li; Chun-Kuan Lu
Journal:  Case Rep Oncol Med       Date:  2018-04-01

5.  Neuroleukemiosis: Two Case Reports.

Authors:  Vlad Voin; Shehzad Khalid; Sebastian Shrager; R Shane Tubbs; Robert Greiner; Krishnamoorthy Thamburaj; Elias Rizk
Journal:  Cureus       Date:  2017-07-31
  5 in total

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