Literature DB >> 19742083

Characterization and pathological characteristics of spontaneous osteonecrosis of the knee.

Simon C Mears1, Edward F McCarthy, Lynne C Jones, David S Hungerford, Michael A Mont.   

Abstract

OBJECTIVE: Spontaneous osteonecrosis of the knee affects patients typically over the age of fifty-five years. Evidence exists that this process may not be true necrosis. The purpose of this study was to characterize the demographic, radiographic, and pathologic features of this condition.
MATERIALS AND METHODS: Twenty-one patients (twenty-two knees) consecutively treated for spontaneous osteonecrosis of the knee were studied.
RESULTS: Only one of twenty-two specimens demonstrated evidence of bone necrosis. No specimens showed fat necrosis, marrow necrosis, fibrous change or appositional bone repair. Fourteen of twenty-two specimens (64%) showed significant osteopenia and fifteen of twenty-two specimens (68%) showed evidence of osteoarthritis.
CONCLUSIONS: This study demonstrated that spontaneous osteonecrosis of the knee is not an osteonecrotic condition and has been misnamed. Osteopenia and osteoarthritis may play a role in the pathogenesis of this disease.

Entities:  

Mesh:

Year:  2009        PMID: 19742083      PMCID: PMC2723690     

Source DB:  PubMed          Journal:  Iowa Orthop J        ISSN: 1541-5457


  12 in total

1.  Spontaneous Osteonecrosis of the Knee.

Authors: 
Journal:  J Am Acad Orthop Surg       Date:  1994-05       Impact factor: 3.020

2.  Spontaneous osteonecrosis of the knee: the result of subchondral insufficiency fracture.

Authors:  T Yamamoto; P G Bullough
Journal:  J Bone Joint Surg Am       Date:  2000-06       Impact factor: 5.284

3.  Idiopathic bone necrosis of the femoral head. Early diagnosis and treatment.

Authors:  R P Ficat
Journal:  J Bone Joint Surg Br       Date:  1985-01

4.  Radiologic case study. Spontaneous osteonecrosis of the knee reclassified as insufficiency fracture.

Authors:  Arif S Kidwai; Shane D Hemphill; Harry J Griffiths
Journal:  Orthopedics       Date:  2005-03       Impact factor: 1.390

5.  Spontaneous osteonecrosis of the knee: biochemical markers of bone turnover and pathohistology.

Authors:  C E Berger; A Kröner; K H Kristen; M Minai-Pour; T Leitha; A Engel
Journal:  Osteoarthritis Cartilage       Date:  2005-08       Impact factor: 6.576

6.  Idiopathic osteonecrosis of the knee. Aetiology, prognosis and treatment.

Authors:  P Aglietti; J N Insall; R Buzzi; G Deschamps
Journal:  J Bone Joint Surg Br       Date:  1983-11

7.  [Aseptic necrosis of the femur head. Pathogenesis: the theory of circulation].

Authors:  R P Ficat
Journal:  Acta Orthop Belg       Date:  1981 Mar-Apr       Impact factor: 0.500

8.  MR appearance of SONK-like subchondral abnormalities in the adult knee: SONK redefined.

Authors:  R Richard Ramnath; Susan V Kattapuram
Journal:  Skeletal Radiol       Date:  2004-07-13       Impact factor: 2.199

9.  Osteonecrosis of the knee. A clinicopathological study in twenty-eight patients.

Authors:  S C Ahuja; P G Bullough
Journal:  J Bone Joint Surg Am       Date:  1978-03       Impact factor: 5.284

Review 10.  Spontaneous osteonecrosis of the knee associated with tibial plateau and femoral condyle insufficiency stress fracture.

Authors:  J A Narváez; J Narváez; E De Lama; A Sánchez
Journal:  Eur Radiol       Date:  2002-12-19       Impact factor: 5.315

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  20 in total

1.  Intra-operative femoral condylar stress during arthroscopy: an in vivo biomechanical assessment.

Authors:  Rahel B Schmid; Dieter Wirz; Beat Göpfert; Markus P Arnold; Niklaus F Friederich; Michael T Hirschmann
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2010-12-11       Impact factor: 4.342

2.  Histopathologic findings of spontaneous osteonecrosis of the knee at an early stage: a case report.

Authors:  Hiroyuki Hatanaka; Takuaki Yamamoto; Goro Motomura; Kazuhiko Sonoda; Yukihide Iwamoto
Journal:  Skeletal Radiol       Date:  2016-01-14       Impact factor: 2.199

3.  Overlapping features of rapidly progressive osteoarthrosis and Charcot arthropathy.

Authors:  Takashi Sono; Carolyn A Meyers; Daniel Miller; Catherine Ding; Edward F McCarthy; Aaron W James
Journal:  J Orthop       Date:  2019-03-12

4.  Thrombophilia-Associated Factors in Patients with Spontaneous Osteonecrosis of the Knee.

Authors:  Niv Marom; Jonathan Ej Koch; Yiftah Beer; Martin Ellis; Gil Ganot; Meir Nyska; Guy Maoz; Iftach Hetsroni
Journal:  Cartilage       Date:  2018-01-07       Impact factor: 4.634

5.  Femoral condyle insufficiency fractures: associated clinical and morphological findings and impact on outcome.

Authors:  Sara K Plett; Lauren A Hackney; Ursula Heilmeier; Lorenzo Nardo; Aihong Yu; Chiyuan A Zhang; Thomas M Link
Journal:  Skeletal Radiol       Date:  2015-08-20       Impact factor: 2.199

Review 6.  Osteonecrosis of the knee: review.

Authors:  Ammar R Karim; Jeffrey J Cherian; Julio J Jauregui; Todd Pierce; Michael A Mont
Journal:  Ann Transl Med       Date:  2015-01

7.  Subchondral insufficiency fracture of the knee: grading, risk factors, and outcome.

Authors:  Samia Sayyid; Yara Younan; Gulshan Sharma; Adam Singer; William Morrison; Adam Zoga; Felix M Gonzalez
Journal:  Skeletal Radiol       Date:  2019-06-27       Impact factor: 2.199

Review 8.  Magnetic resonance imaging of subchondral insufficiency fractures of the lower limb.

Authors:  Sangoh Lee; Asif Saifuddin
Journal:  Skeletal Radiol       Date:  2019-01-31       Impact factor: 2.199

9.  Subchondral osteopenia and accelerated bone remodelling post-ovariectomy - a possible mechanism for subchondral microfractures in the aetiology of spontaneous osteonecrosis of the knee?

Authors:  J C Holland; O Brennan; O D Kennedy; S Rackard; F J O'Brien; T C Lee
Journal:  J Anat       Date:  2012-11-21       Impact factor: 2.610

10.  A Retrospective Study of Unicompartmental Knee Arthroplasty Functional Outcome and the Incidence of Medial Meniscus Posterior Root Tear in Spontaneous Osteonecrosis of the Knee.

Authors:  Po-Ju Wu; Tsung Yu Lin; Yung Chang Lu
Journal:  Biomed Res Int       Date:  2021-04-30       Impact factor: 3.411

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