OBJECTIVE: The Mental Adjustment to Cancer Scale (MAC scale) has evolved to a standard measure in the field of psycho-oncology. In this context an attitude called "fighting spirit" gained much attention as a coping style. Some reports suggest that coping efforts as measured by the MAC scale are predictive for survival of breast cancer patients. We explored the predictive power of the MAC scale by using a sample of patients with haematological malignancies undergoing allogenic hemopoietic stem cell transplantation (HSCT). METHODS: Between 9/1999 and 12/2001 127 patients were administered the MAC scale prior to HSCT. Follow-up data of overall survival and event-free survival were obtained in December 2003 and analyzed using Cox-regression models. RESULTS: At the time of the follow-up, 68 patients had died (overall survival), 75 patients had experienced a relapse or had died (event-free survival). We failed to find significant results for the MAC subscales with and without adjustment for prognostic factors. CONCLUSION: In the special situation of patients facing HSCT the MAC scale seems not to be of predictive value. In general, with respect to survival the empirical evidence is not very convincing.
OBJECTIVE: The Mental Adjustment to Cancer Scale (MAC scale) has evolved to a standard measure in the field of psycho-oncology. In this context an attitude called "fighting spirit" gained much attention as a coping style. Some reports suggest that coping efforts as measured by the MAC scale are predictive for survival of breast cancerpatients. We explored the predictive power of the MAC scale by using a sample of patients with haematological malignancies undergoing allogenic hemopoietic stem cell transplantation (HSCT). METHODS: Between 9/1999 and 12/2001 127 patients were administered the MAC scale prior to HSCT. Follow-up data of overall survival and event-free survival were obtained in December 2003 and analyzed using Cox-regression models. RESULTS: At the time of the follow-up, 68 patients had died (overall survival), 75 patients had experienced a relapse or had died (event-free survival). We failed to find significant results for the MAC subscales with and without adjustment for prognostic factors. CONCLUSION: In the special situation of patients facing HSCT the MAC scale seems not to be of predictive value. In general, with respect to survival the empirical evidence is not very convincing.
Authors: Mohamed L Sorror; Michael B Maris; Rainer Storb; Frederic Baron; Brenda M Sandmaier; David G Maloney; Barry Storer Journal: Blood Date: 2005-06-30 Impact factor: 22.113
Authors: A Gratwohl; J Hermans; J M Goldman; W Arcese; E Carreras; A Devergie; F Frassoni; G Gahrton; H J Kolb; D Niederwieser; T Ruutu; J P Vernant; T de Witte; J Apperley Journal: Lancet Date: 1998-10-03 Impact factor: 79.321
Authors: Ning Deng; Yue Zhang; Zhihai Ma; Richard Lin; Tzu-Hao Cheng; Hua Tang; Michael P Snyder; Stanley N Cohen Journal: NAR Genom Bioinform Date: 2022-07-27