Literature DB >> 19740022

Decreased monoamine oxidase (MAO) activity and MAO-A expression as diagnostic indicators of human esophageal cancers.

Bingye Yang1, Jie Jiang, Haoxin Du, Guojun Geng, Zhen Jiang, Chengcai Yao, Qiqing Zhang, Lihua Jin.   

Abstract

Human esophageal cancer is a common occurring malignancy with high mortality rate partially due to lack of tools for early diagnosis. In this study, we have analysed tumour tissue from 50 cases of primary esophageal cancer. Our studies showed that the activity of monoamine oxidase (MAO) and the expression of MAO-A were strikingly decreased in the tumour tissues of 48 (96%) and 44 (88%) patients, respectively. These results suggest that the activity of MAO and the expression of MAO-A may be used as new diagnostic markers for esophageal cancers.

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Year:  2009        PMID: 19740022     DOI: 10.3109/13547500903207688

Source DB:  PubMed          Journal:  Biomarkers        ISSN: 1354-750X            Impact factor:   2.658


  4 in total

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Authors:  Hui Min Lee; Alice Pei Eal Sia; Lili Li; Hans Prakash Sathasivam; Melissa Sue Ann Chan; Pathmanathan Rajadurai; Chi Man Tsang; Sai Wah Tsao; Paul G Murray; Qian Tao; Ian C Paterson; Lee Fah Yap
Journal:  Sci Rep       Date:  2020-04-09       Impact factor: 4.379

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Authors:  Giuseppina Roscigno; Iolanda Scognamiglio; Francesco Ingenito; Rosario Vincenzo Chianese; Francesco Palma; Alan Chan; Gerolama Condorelli
Journal:  Cancers (Basel)       Date:  2020-12-13       Impact factor: 6.639

3.  Differential expression of IL-6/IL-6R and MAO-A regulates invasion/angiogenesis in breast cancer.

Authors:  Rashmi Bharti; Goutam Dey; Anjan Kumar Das; Mahitosh Mandal
Journal:  Br J Cancer       Date:  2018-04-26       Impact factor: 7.640

4.  The clinical value and potential molecular mechanism of the downregulation of MAOA in hepatocellular carcinoma tissues.

Authors:  Yu-Yan Pang; Jian-Di Li; Li Gao; Xia Yang; Yi-Wu Dang; Ze-Feng Lai; Li-Min Liu; Jie Yang; Hua-Yu Wu; Rong-Quan He; Zhi-Guang Huang; Dan-Dan Xiong; Li-Hua Yang; Lin Shi; Wei-Jia Mo; Deng Tang; Hui-Ping Lu; Gang Chen
Journal:  Cancer Med       Date:  2020-09-15       Impact factor: 4.452

  4 in total

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