| Literature DB >> 19739652 |
Elias A Couladouros1, Marianna Dakanali, Konstantinos D Demadis, Veroniki P Vidali.
Abstract
A biomimetic approach toward type A polyprenylated acylphloroglucinols (PPAPs) is described. The method is based on a C-alkylation-cation cyclization reaction sequence, leading to a convenient buildup of molecular complexity, employing the simple and readily available deoxycohumulone and an appropriately functionalized hydroxy halide. Thus, a versatile construction of the fully functionalized bicyclic framework of type A PPAPs (5) was achieved.Entities:
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Year: 2009 PMID： 19739652 DOI： 10.1021/ol901781n
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005