| Literature DB >> 19739609 |
Guillaume Cantagrel1, Benoît de Carné-Carnavalet, Christophe Meyer, Janine Cossy.
Abstract
Iron trichloride promotes the cationic cyclization of o-(arylethynyl)aryl isocyanates leading to 3-(arylchloromethylene)oxindoles which can be stereoselectively converted to (Z)-3-(aminomethylene)oxindoles under straightforward conditions. When the alkyne is substituted by an alkyl group, activation of the allylic C-H bond also occurs producing 1,2-(dichloroalkylidene)oxindoles.Entities:
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Year: 2009 PMID： 19739609 DOI： 10.1021/ol9014877
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005