| Literature DB >> 19739600 |
Masahiko Isaka1, Somporn Palasarn, Sanisa Lapanun, Rungtiwa Chanthaket, Nattawut Boonyuen, Saisamorn Lumyong.
Abstract
Two new gamma-lactones, eutypellins A (1) and B (2), and two ent-eudesmane sesquiterpenes, ent-4(15)-eudesmen-11-ol-1-one (3) and ent-4(15)-eudesmen-1alpha,11-diol (4), together with three known pimarane diterpenes, diaporthein B, scopararane A, and libertellenone C, were isolated from the endophytic fungus Eutypella sp. BCC 13199. The structures of these compounds were elucidated by interpretation of spectroscopic data. The absolute configuration of 4 was confirmed by application of the modified Mosher's method. Eutypellin A (1) and sesquiterpene 3 exhibited weak cytotoxic activities.Entities:
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Year: 2009 PMID: 19739600 DOI: 10.1021/np900316x
Source DB: PubMed Journal: J Nat Prod ISSN: 0163-3864 Impact factor: 4.050