Literature DB >> 19737889

Occurrence of physiologic gaze-evoked nystagmus at small angles of gaze.

Chad A Whyte1, Anne Marie Petrock, Michael Rosenberg.   

Abstract

PURPOSE: Physiologic gaze-evoked nystagmus (GEN) is one of many normal eye movements seen on the neurologic examination. GEN occurring at gaze angles >45 degrees is considered a positive sign in the Horizontal Gaze Nystagmus Test (HGNT) used by United States police officers to determine alcohol intoxication.
METHODS: The authors enrolled 56 subjects after a brief survey and a neurologic examination yielding normal
RESULTS: Subjects were directed to look at small targets on the wall in primary gaze and at 10 degrees intervals until they reached extreme gaze bilaterally. Eye movements were recorded using infrared video-oculography.
RESULTS: In addition to a high incidence of physiologic GEN at gaze angles 30 degrees and greater (at 30 degrees, n = 43%; at 40 degrees, n = 73%; at extreme gaze, n = 93%), the authors demonstrated that physiologic GEN occurs at smaller gaze angles (at 10 degrees, n = 21%; at 20 degrees, n = 34%).
CONCLUSIONS: A significant number of subjects with normal vision have physiologic GEN at gaze angles as small as 10 degrees. This could potentially refute the "failing" grade that is the hallmark of the HGNT and propagates further testing of the validity of this test in the conviction of intoxicated drivers.

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Year:  2009        PMID: 19737889     DOI: 10.1167/iovs.08-3241

Source DB:  PubMed          Journal:  Invest Ophthalmol Vis Sci        ISSN: 0146-0404            Impact factor:   4.799


  7 in total

1.  Gaze-evoked nystagmus induced by alcohol intoxication.

Authors:  Fausto Romano; Alexander A Tarnutzer; Dominik Straumann; Stefano Ramat; Giovanni Bertolini
Journal:  J Physiol       Date:  2017-01-17       Impact factor: 5.182

2.  Cerebellar Rebound Nystagmus Explained as Gaze-Evoked Nystagmus Relative to an Eccentric Set Point: Implications for the Clinical Examination.

Authors:  Giovanni Bertolini; Alexander A Tarnutzer; Stefan Yu Bögli; Dominik Straumann; Bernhard Schuknecht
Journal:  Cerebellum       Date:  2021-10       Impact factor: 3.847

3.  Stochastic Physiological Gaze-Evoked Nystagmus With Slow Centripetal Drift During Fixational Eye Movements at Small Gaze Eccentricities.

Authors:  Makoto Ozawa; Yasuyuki Suzuki; Taishin Nomura
Journal:  Front Hum Neurosci       Date:  2022-05-12       Impact factor: 3.473

4.  Sensorimotor adaptation as a behavioural biomarker of early spinocerebellar ataxia type 6.

Authors:  Muriel T N Panouillères; Raed A Joundi; Sonia Benitez-Rivero; Binith Cheeran; Christopher R Butler; Andrea H Németh; R Chris Miall; Ned Jenkinson
Journal:  Sci Rep       Date:  2017-05-24       Impact factor: 4.379

5.  Dose-dependent sensorimotor impairment in human ocular tracking after acute low-dose alcohol administration.

Authors:  Terence L Tyson; Nathan H Feick; Patrick F Cravalho; Erin E Flynn-Evans; Leland S Stone
Journal:  J Physiol       Date:  2020-12-17       Impact factor: 5.182

6.  Gaze holding in healthy subjects.

Authors:  Giovanni Bertolini; Alexander A Tarnutzer; Itsaso Olasagasti; Elham Khojasteh; Konrad P Weber; Christopher J Bockisch; Dominik Straumann; Sarah Marti
Journal:  PLoS One       Date:  2013-04-26       Impact factor: 3.240

7.  Prevalence and Characteristics of Physiological Gaze-Evoked and Rebound Nystagmus: Implications for Testing Their Pathological Counterparts.

Authors:  Michelle Sari Ritter; Giovanni Bertolini; Dominik Straumann; Stefan Yu Bögli
Journal:  Front Neurol       Date:  2020-10-22       Impact factor: 4.003

  7 in total

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