| Literature DB >> 19737509 |
Mark Shackleton1, Elsa Quintana, Eric R Fearon, Sean J Morrison.
Abstract
The identification and characterization of cancer stem cells might lead to more effective treatments for some cancers by focusing therapy on the most malignant cells. To achieve this goal it will be necessary to determine which cancers follow a cancer stem cell model and which do not, to address technical issues related to tumorigenesis assays, and to test the extent to which cancer cell heterogeneity arises from genetic versus epigenetic differences.Entities:
Mesh：
Year: 2009 PMID： 19737509 DOI： 10.1016/j.cell.2009.08.017
Source DB: PubMed Journal: Cell ISSN： 0092-8674 Impact factor: 41.582