BACKGROUND: A special form of epileptic seizures (ES) is the life-threatening condition of status epilepticus (SE), which requires immediate and specific treatment based on a correct diagnosis of the underlying disease condition. HYPOTHESIS/ OBJECTIVES: The objectives of this retrospective study were to determine prevalence of ES and SE in dogs presenting at a veterinary teaching hospital, to identify the etiology and relative risk (RR) for SE in general and at the onset of seizures. Furthermore the outcome for dogs suffering from SE was to be evaluated. ANIMALS: Three hundred and ninety-four dogs that were admitted to a veterinary teaching hospital (January 1, 2002 to March 31, 2008) with ES. METHODS: All medical records of dogs with ES were identified by screening the clinical documentation system and evaluated for inclusion in this retrospective study. RESULTS: Dogs with reactive seizures caused by poisoning had a significantly higher risk of developing SE (P < .001; RR = 2.74), particularly as 1st manifestation of a seizure disorder (P = .001; RR = 1.97). After SE, dogs with symptomatic epilepsy had a significantly lower probability of survival than dogs with idiopathic epilepsy (P < .001) and reactive ESs (P= .005). CONCLUSION AND CLINICAL IMPORTANCE: In dogs showing SE as the 1st manifestation of a seizure disorder, intoxication should always be considered and appropriate investigations undertaken. Dogs with SE owing to toxicosis have more favorable outcomes than dogs with symptomatic epilepsy (P < .001).
BACKGROUND: A special form of epileptic seizures (ES) is the life-threatening condition of status epilepticus (SE), which requires immediate and specific treatment based on a correct diagnosis of the underlying disease condition. HYPOTHESIS/ OBJECTIVES: The objectives of this retrospective study were to determine prevalence of ES and SE in dogs presenting at a veterinary teaching hospital, to identify the etiology and relative risk (RR) for SE in general and at the onset of seizures. Furthermore the outcome for dogs suffering from SE was to be evaluated. ANIMALS: Three hundred and ninety-four dogs that were admitted to a veterinary teaching hospital (January 1, 2002 to March 31, 2008) with ES. METHODS: All medical records of dogs with ES were identified by screening the clinical documentation system and evaluated for inclusion in this retrospective study. RESULTS:Dogs with reactive seizures caused by poisoning had a significantly higher risk of developing SE (P < .001; RR = 2.74), particularly as 1st manifestation of a seizure disorder (P = .001; RR = 1.97). After SE, dogs with symptomatic epilepsy had a significantly lower probability of survival than dogs with idiopathic epilepsy (P < .001) and reactive ESs (P= .005). CONCLUSION AND CLINICAL IMPORTANCE: In dogs showing SE as the 1st manifestation of a seizure disorder, intoxication should always be considered and appropriate investigations undertaken. Dogs with SE owing to toxicosis have more favorable outcomes than dogs with symptomatic epilepsy (P < .001).
Authors: Luisa De Risio; Sofie Bhatti; Karen Muñana; Jacques Penderis; Veronika Stein; Andrea Tipold; Mette Berendt; Robyn Farqhuar; Andrea Fischer; Sam Long; Paul J J Mandigers; Kaspar Matiasek; Rowena M A Packer; Akos Pakozdy; Ned Patterson; Simon Platt; Michael Podell; Heidrun Potschka; Martí Pumarola Batlle; Clare Rusbridge; Holger A Volk Journal: BMC Vet Res Date: 2015-08-28 Impact factor: 2.741
Authors: Velia-Isabel Hülsmeyer; Andrea Fischer; Paul J J Mandigers; Luisa DeRisio; Mette Berendt; Clare Rusbridge; Sofie F M Bhatti; Akos Pakozdy; Edward E Patterson; Simon Platt; Rowena M A Packer; Holger A Volk Journal: BMC Vet Res Date: 2015-08-28 Impact factor: 2.741
Authors: Irene Vuu; Lisa D Coles; Patricia Maglalang; Ilo E Leppik; Greg Worrell; Daniel Crepeau; Usha Mishra; James C Cloyd; Edward E Patterson Journal: Front Vet Sci Date: 2016-12-05
Authors: Chelsie M Estey; Curtis W Dewey; Mark Rishniw; David M Lin; Jennifer Bouma; Joseph Sackman; Erica Burkland Journal: Front Vet Sci Date: 2017-11-08
Authors: M Charalambous; S F M Bhatti; L Van Ham; S Platt; N D Jeffery; A Tipold; J Siedenburg; H A Volk; D Hasegawa; A Gallucci; G Gandini; M Musteata; E Ives; A E Vanhaesebrouck Journal: J Vet Intern Med Date: 2017-05-24 Impact factor: 3.333
Authors: S Long; S Frey; D R Freestone; M LeChevoir; P Stypulkowski; J Giftakis; M Cook Journal: J Vet Intern Med Date: 2013-11-16 Impact factor: 3.333