Literature DB >> 19737134

Chemical synthesis of oligonucleotides using acetone as a washing solvent.

Paul Gaytán1.   

Abstract

Acetone is being proposed as the main washing solvent during automated synthesis of oligonucleotides to reduce acetonitrile usage in the assembly process and endure the impact of global acetonitrile shortage.

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Year:  2009        PMID： 19737134     DOI： 10.2144/000113206

Source DB:  PubMed          Journal:  Biotechniques        ISSN： 0736-6205            Impact factor:   1.993


  2 in total

1.  Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing.

Authors:  Benjamin I Andrews; Firoz D Antia; Shawn B Brueggemeier; Louis J Diorazio; Stefan G Koenig; Michael E Kopach; Heewon Lee; Martin Olbrich; Anna L Watson
Journal:  J Org Chem       Date:  2020-11-30       Impact factor: 4.354

2.  Terminator-free template-independent enzymatic DNA synthesis for digital information storage.

Authors:  Henry H Lee; Reza Kalhor; Naveen Goela; Jean Bolot; George M Church
Journal:  Nat Commun       Date:  2019-06-03       Impact factor: 14.919
  2 in total

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