Literature DB >> 19737064

Escherichia coli O157:H7 vaccine dose-effect in feedlot cattle.

Rodney A Moxley1, David R Smith, Matt Luebbe, Galen E Erickson, Terry J Klopfenstein, Dragan Rogan.   

Abstract

A clinical trial conducted during the summer of 2006 evaluated effects of two- and three-dose regimens of an Escherichia coli O157 vaccine product on the probability of detecting E. coli O157:H7 in feces and colonization of the terminal rectum. The three-dose regimen significantly reduced the probability for cattle to shed E. coli O157:H7 in feces 65% compared to placebo-treated cattle. A dose-effect was demonstrated because a two-dose regimen of the vaccine product was intermediate in effect. These results are consistent with previous estimates of vaccine efficacy against fecal shedding, and agree with our previous finding that efficacy of two or three doses of this vaccine product exhibit a dose-response.

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Year:  2009        PMID： 19737064     DOI： 10.1089/fpd.2009.0297

Source DB:  PubMed          Journal:  Foodborne Pathog Dis        ISSN： 1535-3141            Impact factor:   3.171


  9 in total

1.  Vaccination with type III secreted proteins leads to decreased shedding in calves after experimental infection with Escherichia coli O157.

Authors:  Kevin J Allen; Dragan Rogan; B Brett Finlay; Andrew A Potter; David J Asper
Journal:  Can J Vet Res       Date:  2011-04       Impact factor: 1.310

2.  Insights into mucosal innate responses to Escherichia coli O157 : H7 colonization of cattle by mathematical modelling of excretion dynamics.

Authors:  Michael J Tildesley; David L Gally; Tom N McNeilly; J Chris Low; Arvind Mahajan; Nicholas J Savill
Journal:  J R Soc Interface       Date:  2011-08-17       Impact factor: 4.118

3.  Regional immune response to immunization with Escherichia coli O157:H7-derived intimin in cattle.

Authors:  Kathryn G Boland; Andrea N Hayles; Claire B Miller; Tovah Kerr; Wendy C Brown; Kevin K Lahmers
Journal:  Clin Vaccine Immunol       Date:  2013-02-13

4.  Passive immunization by recombinant ferric enterobactin protein (FepA) from Escherichia coli O157.

Authors:  Seyed Mehdi Larrie-Bagha; Iraj Rasooli; Seyed Latif Mousavi-Gargari; Zohreh Rasooli; Shahram Nazarian
Journal:  Iran J Microbiol       Date:  2013-06

Review 5.  Mouse models of Escherichia coli O157:H7 infection and shiga toxin injection.

Authors:  Krystle L Mohawk; Alison D O'Brien
Journal:  J Biomed Biotechnol       Date:  2011-01-03

6.  Optimizing the Protection of Cattle against Escherichia coli O157:H7 Colonization through Immunization with Different Combinations of H7 Flagellin, Tir, Intimin-531 or EspA.

Authors:  Tom N McNeilly; Mairi C Mitchell; Alexander Corbishley; Mintu Nath; Hannah Simmonds; Sean P McAteer; Arvind Mahajan; J Christopher Low; David G E Smith; John F Huntley; David L Gally
Journal:  PLoS One       Date:  2015-05-28       Impact factor: 3.240

7.  Immunization with H7-HCP-tir-intimin significantly reduces colonization and shedding of Escherichia coli O157:H7 in goats.

Authors:  Xuehan Zhang; Zhengyu Yu; Shuping Zhang; Kongwang He
Journal:  PLoS One       Date:  2014-03-14       Impact factor: 3.240

8.  Rectal single dose immunization of mice with Escherichia coli O157:H7 bacterial ghosts induces efficient humoral and cellular immune responses and protects against the lethal heterologous challenge.

Authors:  Ulrike Beate Mayr; Pavol Kudela; Alena Atrasheuskaya; Eugenij Bukin; Georgy Ignatyev; Werner Lubitz
Journal:  Microb Biotechnol       Date:  2011-11-22       Impact factor: 5.813

9.  Antibodies Directed against Shiga-Toxin Producing Escherichia coli Serotype O103 Type III Secreted Proteins Block Adherence of Heterologous STEC Serotypes to HEp-2 Cells.

Authors:  Taseen S Desin; Hugh G Townsend; Andrew A Potter
Journal:  PLoS One       Date:  2015-10-09       Impact factor: 3.240
  9 in total

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