Alan Richardson1, Peter Watt, Neil Maxwell. 1. University of Brighton, Chelsea School Reseasrch Centre, Eastbourne, United Kingdom. a.j.richardson@brighton.ac.uk
Abstract
OBJECTIVE: The effect hydration status has on exposure to hypoxia is unclear. The purpose of the study was to identify how hydration status, above and below euhydrated levels, affects the physiological responses and onset of acute mountain sickness symptoms during acute normobaric hypoxia. METHODS:Eight males completedintermittent walking tests under normobaric hypoxic conditions (FIo2 = 0.13) after controlled hyperhydration, hypohydration, and euhydration protocols. A range of physiological, psychological, and altitude illness markers were monitored throughout the 125-minute exposure. RESULTS:Heart rate, core temperature, peripheral arterial oxygen saturation, urine osmolality, and mean self-reported Lake LouiseQuestionnaire acute mountain sickness scores were significantly different between euhydration, hypohydration, and hyperhydration, respectively, and closely correlated with environmental symptoms questionnaire, Lake Louise questionnaire, and headache scores (P < .05). Other measures of ventilation and lung function were also significantly different between hydration conditions (P < .05). CONCLUSIONS:Hydration state above and below euhydration has detrimental consequences on physiological strain and onset of acute mountain sickness symptoms when exposed to acute normobaric hypoxia.
RCT Entities:
OBJECTIVE: The effect hydration status has on exposure to hypoxia is unclear. The purpose of the study was to identify how hydration status, above and below euhydrated levels, affects the physiological responses and onset of acute mountain sickness symptoms during acute normobaric hypoxia. METHODS: Eight males completed intermittent walking tests under normobaric hypoxic conditions (FIo2 = 0.13) after controlled hyperhydration, hypohydration, and euhydration protocols. A range of physiological, psychological, and altitude illness markers were monitored throughout the 125-minute exposure. RESULTS: Heart rate, core temperature, peripheral arterial oxygen saturation, urine osmolality, and mean self-reported Lake Louise Questionnaire acute mountain sickness scores were significantly different between euhydration, hypohydration, and hyperhydration, respectively, and closely correlated with environmental symptoms questionnaire, Lake Louise questionnaire, and headache scores (P < .05). Other measures of ventilation and lung function were also significantly different between hydration conditions (P < .05). CONCLUSIONS: Hydration state above and below euhydration has detrimental consequences on physiological strain and onset of acute mountain sickness symptoms when exposed to acute normobaric hypoxia.
Authors: Erich Hohenauer; Livia Freitag; Miriam Herten; Julia Siallagan; Elke Pollock; Wolfgang Taube; Ron Clijsen Journal: Front Physiol Date: 2022-06-16 Impact factor: 4.755
Authors: Hannes Gatterer; Maria Wille; Martin Faulhaber; Henry Lukaski; Andreas Melmer; Christoph Ebenbichler; Martin Burtscher Journal: PLoS One Date: 2013-08-27 Impact factor: 3.240
Authors: Giacomo Strapazzon; Matiram Pun; Tomas Dal Cappello; Emily Procter; Piergiorgio Lochner; Hermann Brugger; Antonio Piccoli Journal: High Alt Med Biol Date: 2017-10-16 Impact factor: 1.981
Authors: Ivo B Regli; Rachel Turner; Simon Woyke; Simon Rauch; Hermann Brugger; Hannes Gatterer Journal: Int J Environ Res Public Health Date: 2021-05-20 Impact factor: 3.390