| Literature DB >> 19736920 |
Ileana I Rodríguez1, Abimael D Rodríguez, Hong Zhao.
Abstract
A marine metabolite based on a previously undescribed carbon skeleton, aberrarone (1), is reported as a natural product from the Caribbean sea whip, Pseudopterogorgia elisabethae. The molecular structure of the crystalline metabolite was established by spectral analysis and subsequently confirmed by X-ray crystallographic analysis. Aberrarone shows in vitro antimalarial activity against a chloroquine-resistant strain of the protozoan parasite Plasmodium falciparum.Entities:
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Year: 2009 PMID： 19736920 PMCID： PMC2764255 DOI： 10.1021/jo901578r
Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354