Literature DB >> 19735671

Identification of okadaic acid production in the marine dinoflagellate Prorocentrum rhathymum from Florida Bay.

Tianying An1, Jamie Winshell, Gloria Scorzetti, Jack W Fell, Kathleen S Rein.   

Abstract

Extracts of fifty-seven newly isolated strains of dinoflagellates and raphidophytes were screened for protein phosphatase (PP2A) inhibition. Five strains, identified by rDNA sequence analysis as Prorocentrum rhathymum, tested positive and the presence of okadaic acid was confirmed in one strain by HPLC-MS/MS and by HPLC with fluorescence detection and HPLC-MS of the okadaic acid ADAM derivative. Quantitation of the ADAM derivative indicated that the concentration of okadaic acid in the culture medium is 0.153 microg/L. Copyright 2009 Elsevier Ltd. All rights reserved.

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Year:  2009        PMID： 19735671      PMCID： PMC2813983          DOI： 10.1016/j.toxicon.2009.08.018

Source DB:  PubMed          Journal:  Toxicon        ISSN： 0041-0101            Impact factor:   3.033


  15 in total

1.  Improved method for preparation and use of 9-anthryldiazomethane for derivatization of hydroxycarboxylic acids. Application to diarrhetic shellfish poisoning toxins.

Authors:  M A Quilliam; A Gago-Martínez; J A Rodríguez-Vázquez
Journal:  J Chromatogr A       Date:  1998-05-22       Impact factor: 4.759

2.  Okadaic acid production from the marine dinoflagellate Prorocentrum belizeanum Faust isolated from the Belizean coral reef ecosystem.

Authors:  S L Morton; P D Moeller; K A Young; B Lanoue
Journal:  Toxicon       Date:  1998-01       Impact factor: 3.033

3.  Isolation of a new okadaic acid analogue from phytoplankton implicated in diarrhetic shellfish poisoning.

Authors:  R Draisci; L Giannetti; L Lucentini; C Marchiafava; K J James; A G Bishop; B M Healy; S S Kelly
Journal:  J Chromatogr A       Date:  1998-03-06       Impact factor: 4.759

4.  Extraction of microalgal toxins by large-scale pumping of seawater in Spain and Norway, and isolation of okadaic acid and dinophysistoxin-2.

Authors:  Thomas Rundberget; Morten Sandvik; Kristofer Larsen; Gemita M Pizarro; Beatriz Reguera; Tonje Castberg; Eli Gustad; Jared I Loader; Frode Rise; Alistair L Wilkins; Christopher O Miles
Journal:  Toxicon       Date:  2007-07-27       Impact factor: 3.033

5.  Identification of okadaic acid from a Caribbean dinoflagellate, Prorocentrum concavum.

Authors:  R W Dickey; S C Bobzin; D J Faulkner; F A Bencsath; D Andrzejewski
Journal:  Toxicon       Date:  1990       Impact factor: 3.033

6.  Evidence of okadaic acid production in a cultured strain of the marine dinoflagellate Prorocentrum rhathymum from Malaysia.

Authors:  A Caillaud; P de la Iglesia; M Campàs; L Elandaloussi; M Fernández; N Mohammad-Noor; K Andree; J Diogène
Journal:  Toxicon       Date:  2009-07-23       Impact factor: 3.033

7.  Characterization of fatty acid esters of okadaic acid and related toxins in blue mussels (Mytilus edulis) from Norway.

Authors:  Trine Torgersen; Alistair L Wilkins; Thomas Rundberget; Christopher O Miles
Journal:  Rapid Commun Mass Spectrom       Date:  2008-04       Impact factor: 2.419

Review 8.  Okadaic acid: the archetypal serine/threonine protein phosphatase inhibitor.

Authors:  A B Dounay; C J Forsyth
Journal:  Curr Med Chem       Date:  2002-11       Impact factor: 4.530

9.  Multiple simultaneous detection of Harmful Algal Blooms (HABs) through a high throughput bead array technology, with potential use in phytoplankton community analysis.

Authors:  G Scorzetti; L E Brand; G L Hitchcock; K S Rein; C D Sinigalliano; J W Fell
Journal:  Harmful Algae       Date:  2009       Impact factor: 4.273

10.  Highly sensitive assay of okadaic acid using protein phosphatase and paranitrophenyl phosphate.

Authors:  J F Simon; J P Vernoux
Journal:  Nat Toxins       Date:  1994
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  9 in total

1.  Fluorometric determination of okadaic acid using a truncated aptamer.

Authors:  Raja Chinnappan; Razan AlZabn; Tanveer Ahmad Mir; Mamoun Bader; Mohammed Zourob
Journal:  Mikrochim Acta       Date:  2019-06-10       Impact factor: 5.833

2.  The structures of three metabolites of the algal hepatotoxin okadaic acid produced by oxidation with human cytochrome P450.

Authors:  Li Liu; Fujiang Guo; Sheila Crain; Michael A Quilliam; Xiaotang Wang; Kathleen S Rein
Journal:  Bioorg Med Chem       Date:  2012-04-28       Impact factor: 3.641

Review 3.  A review on toxic and harmful algae in Greek coastal waters (E. Mediterranean Sea).

Authors:  Lydia Ignatiades; Olympia Gotsis-Skretas
Journal:  Toxins (Basel)       Date:  2010-05-11       Impact factor: 4.546

4.  Detection of Dinophysistoxin-1 in Clonal Culture of Marine Dinoflagellate Prorocentrum foraminosum (Faust M.A., 1993) from the Sea of Japan.

Authors:  Polina A Kameneva; Kseniya V Efimova; Viacheslav G Rybin; Tatiana Y Orlova
Journal:  Toxins (Basel)       Date:  2015-09-28       Impact factor: 4.546

5.  Effects of substratum and depth on benthic harmful dinoflagellate assemblages.

Authors:  Li Keat Lee; Zhen Fei Lim; Haifeng Gu; Leo Lai Chan; R Wayne Litaker; Patricia A Tester; Chui Pin Leaw; Po Teen Lim
Journal:  Sci Rep       Date:  2020-07-09       Impact factor: 4.379

6.  Effect of Suspended Particulate Matter on the Accumulation of Dissolved Diarrhetic Shellfish Toxins by Mussels (Mytilus galloprovincialis) under Laboratory Conditions.

Authors:  Aifeng Li; Meihui Li; Jiangbing Qiu; Jialiang Song; Ying Ji; Yang Hu; Shuqin Wang; Yijia Che
Journal:  Toxins (Basel)       Date:  2018-07-03       Impact factor: 4.546

Review 7.  Industrial Applications of Dinoflagellate Phycotoxins Based on Their Modes of Action: A Review.

Authors:  Kichul Cho; Jina Heo; Jinwook Han; Hyun Dae Hong; Hancheol Jeon; Hyun-Ju Hwang; Chang-Yu Hong; Daekyung Kim; Jong Won Han; Kyunghwa Baek
Journal:  Toxins (Basel)       Date:  2020-12-18       Impact factor: 4.546

Review 8.  Okadaic acid meet and greet: an insight into detection methods, response strategies and genotoxic effects in marine invertebrates.

Authors:  María Verónica Prego-Faraldo; Vanessa Valdiglesias; Josefina Méndez; José M Eirín-López
Journal:  Mar Drugs       Date:  2013-08-09       Impact factor: 5.118

Review 9.  Mixtures of Lipophilic Phycotoxins: Exposure Data and Toxicological Assessment.

Authors:  Jimmy Alarcan; Ronel Biré; Ludovic Le Hégarat; Valérie Fessard
Journal:  Mar Drugs       Date:  2018-01-31       Impact factor: 5.118
  9 in total

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