| Literature DB >> 1973471 |
H Burger1, A L Belman, R Grimson, A Kaell, K Flaherty, J Gulla, R A Gibbs, P N Nguyun, B Weiser.
Abstract
The incubation period of human immunodeficiency virus type 1 (HIV-1) infection was studied in a family of five in which vertical and heterosexual transmission occurred from one index case. This investigation documented incubation periods of longer than 12 years in a mother and her daughter; although neither has symptoms, both are definitely infected and have very low CD4(+)-lymphocyte counts. The study confirmed the predictions of incubation periods longer than 10 years in a small proportion of infected individuals. It provides evidence that vertically HIV-1-infected teenagers can be expected to appear in the population.Entities:
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Year: 1990 PMID: 1973471 DOI: 10.1016/0140-6736(90)91657-v
Source DB: PubMed Journal: Lancet ISSN: 0140-6736 Impact factor: 79.321