Literature DB >> 1973471

Long HIV-1 incubation periods and dynamics of transmission within a family.

H Burger1, A L Belman, R Grimson, A Kaell, K Flaherty, J Gulla, R A Gibbs, P N Nguyun, B Weiser.   

Abstract

The incubation period of human immunodeficiency virus type 1 (HIV-1) infection was studied in a family of five in which vertical and heterosexual transmission occurred from one index case. This investigation documented incubation periods of longer than 12 years in a mother and her daughter; although neither has symptoms, both are definitely infected and have very low CD4(+)-lymphocyte counts. The study confirmed the predictions of incubation periods longer than 10 years in a small proportion of infected individuals. It provides evidence that vertically HIV-1-infected teenagers can be expected to appear in the population.

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Year:  1990        PMID: 1973471     DOI: 10.1016/0140-6736(90)91657-v

Source DB:  PubMed          Journal:  Lancet        ISSN: 0140-6736            Impact factor:   79.321


  3 in total

1.  HIV antibody testing: CMA counselling guidelines.

Authors: 
Journal:  CMAJ       Date:  1990-11-01       Impact factor: 8.262

2.  Evolution of human immunodeficiency virus type 1 nucleotide sequence diversity among close contacts.

Authors:  H Burger; B Weiser; K Flaherty; J Gulla; P N Nguyen; R A Gibbs
Journal:  Proc Natl Acad Sci U S A       Date:  1991-12-15       Impact factor: 11.205

3.  The combination of phylogenetic analysis with epidemiological and serological data to track HIV-1 transmission in a sexual transmission case.

Authors:  Min Chen; Yanling Ma; Chaojun Yang; Li Yang; Huichao Chen; Lijuan Dong; Jie Dai; Manhong Jia; Lin Lu
Journal:  PLoS One       Date:  2015-03-25       Impact factor: 3.240

  3 in total

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