| Literature DB >> 19733533 |
Abstract
Human embryonic stem cells (hESCs) and induced pluripotent stem cells (hiPSCs) can theoretically be converted into any somatic cell type. hESCs and hiPSCs carrying genetic defects can now be produced to model diseases in vitro. We suggest several guiding principles to help ensure an optimal fit between technology and disease.Entities:
Mesh:
Year: 2009 PMID: 19733533 DOI: 10.1016/j.stem.2009.08.010
Source DB: PubMed Journal: Cell Stem Cell ISSN: 1875-9777 Impact factor: 24.633