| Literature DB >> 19733528 |
Christophe Ginestier1, Suling Liu, Max S Wicha.
Abstract
Loss of BRCA1 has been shown to expand breast stem cells. In Nature Medicine, Lim et al. (2009) demonstrate that breast tissue from BRCA1 mutation carriers contains expanded luminal progenitor cells, suggesting a broader role for BRCA1 in mammary development.Entities:
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Year: 2009 PMID: 19733528 DOI: 10.1016/j.stem.2009.08.007
Source DB: PubMed Journal: Cell Stem Cell ISSN: 1875-9777 Impact factor: 24.633