| Literature DB >> 19733439 |
Sydnei Magno da Silva1, Vitor Marcio Ribeiro, Raul Rio Ribeiro, Wagner Luiz Tafuri, Maria Norma Melo, Marilene Suzan Marques Michalick.
Abstract
Dogs are the most important reservoir of Leishmania (L.) infantum, the causal agent of visceral leishmaniasis (VL) in Brazil. Vectorial infection is the main route of transmission of the parasites. This paper reports the first case of vertical transmission of L. infantum in Brazil, confirmed by PCR and immunohistochemistry techniques in samples from spleen and liver of two stillborn pups from a bitch naturally infected with L. infantum in Belo Horizonte city, endemic area of VL. This result confirms the existence of transplacental transmission of Leishmania between dogs, and suggests the need for further studies to determine the rate of occurrence of this fact in endemic areas and what is their role in the epidemiology of the disease.Entities:
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Year: 2009 PMID： 19733439 DOI： 10.1016/j.vetpar.2009.08.011
Source DB: PubMed Journal: Vet Parasitol ISSN： 0304-4017 Impact factor: 2.738