Literature DB >> 19732716

SRC substrate surprise.

G Steven Martin1.   

Abstract

In this issue of Cancer Cell, Lowy and colleagues show that the SH2 domain of tensin-3 is regulated by phosphorylation by Src and that this phosphorylation promotes the oncogenic function of tensin-3. Phosphorylation of the SH2 domain represents a novel mechanism for the regulation of SH2 ligand binding.

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Year:  2009        PMID： 19732716      PMCID： PMC2803084          DOI： 10.1016/j.ccr.2009.08.017

Source DB:  PubMed          Journal:  Cancer Cell        ISSN： 1535-6108            Impact factor:   31.743


  9 in total

Review 1.  Specificity in signal transduction: from phosphotyrosine-SH2 domain interactions to complex cellular systems.

Authors:  Tony Pawson
Journal:  Cell       Date:  2004-01-23       Impact factor: 41.582

Review 2.  Tensin.

Authors:  Su Hao Lo
Journal:  Int J Biochem Cell Biol       Date:  2004-01       Impact factor: 5.085

3.  Presence of an SH2 domain in the actin-binding protein tensin.

Authors:  S Davis; M L Lu; S H Lo; S Lin; J A Butler; B J Druker; T M Roberts; Q An; L B Chen
Journal:  Science       Date:  1991-05-03       Impact factor: 47.728

4.  The Tensin-3 protein, including its SH2 domain, is phosphorylated by Src and contributes to tumorigenesis and metastasis.

Authors:  Xiaolan Qian; Guorong Li; William C Vass; Alex Papageorge; Renard C Walker; Laura Asnaghi; Peter J Steinbach; Giovanna Tosato; Kent Hunter; Douglas R Lowy
Journal:  Cancer Cell       Date:  2009-09-08       Impact factor: 31.743

5.  Tensin2 variant 3 is associated with aggressive tumor behavior in human hepatocellular carcinoma.

Authors:  Judy Wai Ping Yam; Frankie Chi Fat Ko; Chung-Yiu Chan; Tai-On Yau; Edmund Kwok Kwan Tung; Thomas Ho-Yin Leung; Dong-Yan Jin; Irene Oi-Lin Ng
Journal:  Hepatology       Date:  2006-10       Impact factor: 17.425

6.  Regulation of tensin-promoted cell migration by its focal adhesion binding and Src homology domain 2.

Authors:  Huaiyang Chen; Su Hao Lo
Journal:  Biochem J       Date:  2003-03-15       Impact factor: 3.857

7.  Oncogenic inhibition by a deleted in liver cancer gene requires cooperation between tensin binding and Rho-specific GTPase-activating protein activities.

Authors:  Xiaolan Qian; Guorong Li; Holly K Asmussen; Laura Asnaghi; William C Vass; Richard Braverman; Kenneth M Yamada; Nicholas C Popescu; Alex G Papageorge; Douglas R Lowy
Journal:  Proc Natl Acad Sci U S A       Date:  2007-05-15       Impact factor: 11.205

8.  A reciprocal tensin-3-cten switch mediates EGF-driven mammary cell migration.

Authors:  Menachem Katz; Ido Amit; Ami Citri; Tal Shay; Silvia Carvalho; Sara Lavi; Fernanda Milanezi; Ljuba Lyass; Ninette Amariglio; Jasmine Jacob-Hirsch; Nir Ben-Chetrit; Gabi Tarcic; Moshit Lindzen; Roi Avraham; Yi-Chun Liao; Patricia Trusk; Asya Lyass; Gideon Rechavi; Neil L Spector; Su Hao Lo; Fernando Schmitt; Sarah S Bacus; Yosef Yarden
Journal:  Nat Cell Biol       Date:  2007-07-22       Impact factor: 28.824

9.  The phosphotyrosine-independent interaction of DLC-1 and the SH2 domain of cten regulates focal adhesion localization and growth suppression activity of DLC-1.

Authors:  Yi-Chun Liao; Lizhen Si; Ralph W deVere White; Su Hao Lo
Journal:  J Cell Biol       Date:  2006-12-26       Impact factor: 10.539
  9 in total
  1 in total

Review 1.  The blood-testis barrier and its implications for male contraception.

Authors:  C Yan Cheng; Dolores D Mruk
Journal:  Pharmacol Rev       Date:  2011-10-28       Impact factor: 25.468
  1 in total

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